Micro-metastasis and isolated tumour cells: the span between elective neck dissection versus neck observation in early oral cancer.
Lymph node
Metastasis
Neck dissection
Oral cancer
Journal
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
ISSN: 1434-4726
Titre abrégé: Eur Arch Otorhinolaryngol
Pays: Germany
ID NLM: 9002937
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
07
05
2020
accepted:
20
05
2020
pubmed:
30
5
2020
medline:
28
4
2021
entrez:
30
5
2020
Statut:
ppublish
Résumé
Early oral squamous cell carcinoma (SCC) has a propensity for lymph-node metastasis. To address or not to address the neck electively during the ablative surgery has been an ongoing debate. In recent years, some practice-changing trial and systematic reviews have emerged and put to rest the discussion of elective neck dissection versus neck observation. Today elective neck is not a mere staging procedure. It has a definitive survival advantage, but the pathological basis of this advantage has not been elaborated. Understanding this could help answer some of the critical aspects of tumour spread.
Identifiants
pubmed: 32468427
doi: 10.1007/s00405-020-06076-7
pii: 10.1007/s00405-020-06076-7
doi:
Types de publication
Letter
Comment
Langues
eng
Sous-ensembles de citation
IM
Pagination
2659-2660Commentaires et corrections
Type : CommentOn
Type : CommentIn
Références
Ibrahim SA, Ahmed ANA, Elsersy HA, Darahem IMH (2020) Elective neck dissection in T1/T2 oral squamous cell carcinoma with N0 neck: essential or not? A systematic review and meta-analysis. Eur Arch Otorhinolaryngol. https://doi.org/10.1007/s00405-020-05866-3 (published online ahead of print, 2020 Feb 25)
D'Cruz AK, Siddachari RC, Walvekar RR et al (2009) Elective neck dissection for the management of the N0 neck in early cancer of the oral tongue: need for a randomized controlled trial. Head Neck 31(5):618–624. https://doi.org/10.1002/hed.20988
doi: 10.1002/hed.20988
pubmed: 19132717
D’Cruz AK, Vaish R, Kapre N, Dandekar M, Gupta S, Hawaldar R et al (2015) Elective versus therapeutic neck dissection in node-negative oral cancer. N Engl J Med 373(6):521–529
doi: 10.1056/NEJMoa1506007
Hutchinson IL, Ridout F, Cheung S, Shah N, Hardee P, Surwald C et al (2019) Nationwide randomised trial evaluating elective neck dissection for early stage oral cancer (SEND study) with meta-analysis and concurrent real-world cohort. Br J Cancer 121(10):827–836
doi: 10.1038/s41416-019-0587-2
Majumdar KS, Rao VUS, Prasad R, Ramaswamy V, Sinha P, Subash A (2020) Incidence of micrometastasis and isolated tumour cells in clinicopathologically node-negative head and neck squamous cell carcinoma. J Maxillofac Oral Surg 19(1):131–135. https://doi.org/10.1007/s12663-019-01239-4
doi: 10.1007/s12663-019-01239-4
pubmed: 31988576