The risk of preterm birth in vanishing twin: A multicenter prospective cohort study.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2020
2020
Historique:
received:
03
03
2020
accepted:
28
04
2020
entrez:
30
5
2020
pubmed:
30
5
2020
medline:
18
8
2020
Statut:
epublish
Résumé
To evaluate not only the risk of total preterm birth (PTB) but also spontaneous preterm birth (sPTB) and indicated preterm birth (iPTB) in vanishing twin (VT). This is a secondary analysis of a multicenter prospective cohort study. In 12 different healthcare institutions, women with singleton pregnancies were enrolled in early pregnancy and followed up till delivery. A total of 4,746 women were included in the final analysis, and. the frequency of VT was 1.1% (54/4746). VT group had a higher risk for total PTB (PTB<34 weeks, 2.1% vs. 14.8%, p<0.001; PTB<32 weeks, 1.6% vs. 13.0%, p<0.001; PTB<28 weeks, 0.9% vs. 13.0%, p<0.001) than singleton group. The VT group had increased risk for both sPTB and iPTB (<34 weeks, <32 weeks, and <28 weeks), and this increased risk for sPTB and iPTB in VT group remained significant even after controlling for confounders such as maternal age, parity, pre-pregnancy BMI, and mode of conception. Vanishing twin can be an independent risk factor for both sPTB and iPTB when compared with singleton pregnancy.
Identifiants
pubmed: 32470065
doi: 10.1371/journal.pone.0233097
pii: PONE-D-20-04117
pmc: PMC7259660
doi:
Types de publication
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0233097Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
J Korean Med Sci. 2016 Jun;31(6):939-49
pubmed: 27247504
Arch Gynecol Obstet. 2017 Mar;295(3):559-567
pubmed: 28097444
Reprod Biomed Online. 2010 Feb;20(2):256-60
pubmed: 20113963
Am J Obstet Gynecol. 2003 Sep;189(3):861-73
pubmed: 14526331
Obstet Gynecol. 2018 Jun;131(6):1011-1020
pubmed: 29742658
Am J Obstet Gynecol. 2006 Sep;195(3):814-7
pubmed: 16949417
Obstet Gynecol. 2011 Oct;118(4):928-40
pubmed: 21934458
Fertil Steril. 2008 Aug;90(2):310-4
pubmed: 17931633
Am J Reprod Immunol. 2010 Jul 1;64(1):38-57
pubmed: 20331587
Fertil Steril. 2006 Jul;86(1):247-9
pubmed: 16716323
Can J Anaesth. 1996 Dec;43(12):1237-43
pubmed: 8955974
Fertil Steril. 2013 Jul;100(1):116-21
pubmed: 23541408
Am J Obstet Gynecol. 2002 Jan;186(1):77-83
pubmed: 11810089
Semin Neonatol. 2002 Jun;7(3):223-30
pubmed: 12234746
Prenat Diagn. 1986 Jan-Feb;6(1):33-5
pubmed: 2419890
Fertil Steril. 2010 Nov;94(6):2430-2
pubmed: 20400075
Nan Fang Yi Ke Da Xue Xue Bao. 2014 Oct;34(10):1537-40
pubmed: 25345958
Hum Reprod Update. 1998 Mar-Apr;4(2):177-83
pubmed: 9683354
Hum Reprod. 2005 Oct;20(10):2821-9
pubmed: 15979998
Ultrasound Obstet Gynecol. 2006 Oct;28(5):644-52
pubmed: 17001739
Hum Reprod. 2007 Oct;22(10):2707-14
pubmed: 17728356
BMC Pregnancy Childbirth. 2018 Jul 24;18(1):307
pubmed: 30041617
Lancet. 2008 Jan 5;371(9606):75-84
pubmed: 18177778