The Role of Vitamin D Receptor Gene Polymorphisms in Colorectal Cancer Risk.

colorectal cancer polymorphisms toll-like receptors vitamin D receptors

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
27 May 2020
Historique:
received: 28 04 2020
revised: 25 05 2020
accepted: 25 05 2020
entrez: 31 5 2020
pubmed: 31 5 2020
medline: 31 5 2020
Statut: epublish

Résumé

Vitamin D deficiency has been associated with increased colorectal cancer (CRC) incidence risk and mortality. Vitamin D mediates its action through the binding of the vitamin D receptor (VDR), and polymorphisms of the VDR might explain these inverse associations. The aim of the study was the investigation of the relevance of rs731236;

Identifiants

pubmed: 32471257
pii: cancers12061379
doi: 10.3390/cancers12061379
pmc: PMC7352496
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Hellenic Society of Medical Oncology
ID : n/a
Organisme : Gastrointestinal Cancer Study Group
ID : n/a

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Auteurs

Ippokratis Messaritakis (I)

Laboratory of Translational Oncology, Medical School, University of Crete, 70013 Heraklion, Greece.

Asimina Koulouridi (A)

Laboratory of Translational Oncology, Medical School, University of Crete, 70013 Heraklion, Greece.

Maria Sfakianaki (M)

Laboratory of Translational Oncology, Medical School, University of Crete, 70013 Heraklion, Greece.

Konstantinos Vogiatzoglou (K)

Laboratory of Translational Oncology, Medical School, University of Crete, 70013 Heraklion, Greece.

Nikolaos Gouvas (N)

Medical School, University of Cyprus, 20537 Nicosia, Cyprus.

Elias Athanasakis (E)

Department of General Surgery, Heraklion University Hospital, 71110 Heraklion, Greece.

John Tsiaoussis (J)

Department of Anatomy, School of Medicine, University of Crete, 70013 Heraklion, Greece.

Evangelos Xynos (E)

Department of Surgery, Creta Interclinic Hospital of Heraklion, 71305 Heraklion, Greece.

Dimitriοs Mavroudis (D)

Laboratory of Translational Oncology, Medical School, University of Crete, 70013 Heraklion, Greece.
Department of Medical Oncology, University General Hospital of Heraklion, 71110 Heraklion, Greece.

Maria Tzardi (M)

Laboratory of Pathology, University General Hospital of Heraklion, 70013 Heraklion, Greece.

John Souglakos (J)

Laboratory of Translational Oncology, Medical School, University of Crete, 70013 Heraklion, Greece.
Department of Medical Oncology, University General Hospital of Heraklion, 71110 Heraklion, Greece.

Classifications MeSH