Catatonia in Patients with Autism Spectrum Disorder.
Asperger syndrome
Autism
Catatonia
Journal
Child and adolescent psychiatric clinics of North America
ISSN: 1558-0490
Titre abrégé: Child Adolesc Psychiatr Clin N Am
Pays: United States
ID NLM: 9313451
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
entrez:
31
5
2020
pubmed:
31
5
2020
medline:
29
6
2021
Statut:
ppublish
Résumé
Catatonia was first described by Karl Ludwig Kahlbaum in 1874, occurring in association with other psychiatric and medical disorders. However, in the nineteenth century the disorder was incorrectly classified as a subtype of schizophrenia. This misclassification persisted until the publication of DSM-5 in 2013 when important changes were incorporated. Although the etiology is unknown, disrupted gamma-aminobutyric acid has been proposed as the underlying pathophysiological mechanism. Key symptoms can be identified under 3 clinical domains: motor, speech, and behavioral. Benzodiazepines and electroconvulsive therapy are the only known effective treatments. Timely recognition and treatment have important outcome, and sometimes lifesaving, implications.
Identifiants
pubmed: 32471594
pii: S1056-4993(20)30020-1
doi: 10.1016/j.chc.2020.03.001
pii:
doi:
Substances chimiques
Anticonvulsants
0
Benzodiazepines
12794-10-4
Lorazepam
O26FZP769L
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
443-454Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Disclosure N. Ghaziuddin: Royalties from book, Use of Electroconvulsive Therapy in Children and Adolescents. Publisher: Oxford University Press, 2013. M. Ghaziuddin and L. Andersen do not have any disclosures.