Is the probability of pregnancy after ovarian stimulation for IVF associated with serum estradiol levels on the day of triggering final oocyte maturation with hCG? A systematic review and meta-analysis.


Journal

Journal of assisted reproduction and genetics
ISSN: 1573-7330
Titre abrégé: J Assist Reprod Genet
Pays: Netherlands
ID NLM: 9206495

Informations de publication

Date de publication:
Jul 2020
Historique:
received: 24 11 2019
accepted: 01 04 2020
pubmed: 31 5 2020
medline: 11 3 2021
entrez: 31 5 2020
Statut: ppublish

Résumé

The objective of this systematic review and metaanalysis was to examine if the probability of pregnancy after ovarian stimulation for in vitro fertilization (IVF), using GnRH analogues and gonadotrophins is associated with serum estradiol level (Ε Twenty-one studies were eligible for this systematic review, including 19,598 IVF cycles, whereas three studies were eligible for metaanalysis, including 641 IVF cycles. The main outcome measure was achievement of ongoing pregnancy/live birth and, if not available, clinical pregnancy or biochemical pregnancy. Pooling of data showed no differences in the probability of clinical pregnancy between patients with high and low Ε Currently, there is insufficient evidence to support or deny the presence of an association between the probability of pregnancy and serum Ε

Identifiants

pubmed: 32472447
doi: 10.1007/s10815-020-01829-z
pii: 10.1007/s10815-020-01829-z
pmc: PMC7376780
doi:

Substances chimiques

Chorionic Gonadotropin 0
Estradiol 4TI98Z838E

Types de publication

Journal Article Meta-Analysis Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1531-1541

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Auteurs

Glykeria I Karatasiou (GI)

1st Department of Obstetrics and Gynecology, Unit for Human Reproduction, Papageorgiou General Hospital, Medical School, Aristotle University of Thessaloniki, Efkarpia, 56403, Thessaloniki, Greece. karatasiou_glyka@hotmail.com.

J K Bosdou (JK)

1st Department of Obstetrics and Gynecology, Unit for Human Reproduction, Papageorgiou General Hospital, Medical School, Aristotle University of Thessaloniki, Efkarpia, 56403, Thessaloniki, Greece.

C A Venetis (CA)

Centre for Big Data Research in Health & School of Women's and Children's Health, University of New South Wales, Sydney, Australia.

L Zepiridis (L)

1st Department of Obstetrics and Gynecology, Unit for Human Reproduction, Papageorgiou General Hospital, Medical School, Aristotle University of Thessaloniki, Efkarpia, 56403, Thessaloniki, Greece.

K Chatzimeletiou (K)

1st Department of Obstetrics and Gynecology, Unit for Human Reproduction, Papageorgiou General Hospital, Medical School, Aristotle University of Thessaloniki, Efkarpia, 56403, Thessaloniki, Greece.

T B Tarlatzi (TB)

1st Department of Obstetrics and Gynecology, Unit for Human Reproduction, Papageorgiou General Hospital, Medical School, Aristotle University of Thessaloniki, Efkarpia, 56403, Thessaloniki, Greece.
FIVI Fertility &IVF Center, Interbalkan Medical Center, Thessaloniki, Greece.

G Lainas (G)

Eugonia Assisted Reproduction Unit, Athens, Greece.

B C Tarlatzis (BC)

1st Department of Obstetrics and Gynecology, Unit for Human Reproduction, Papageorgiou General Hospital, Medical School, Aristotle University of Thessaloniki, Efkarpia, 56403, Thessaloniki, Greece.

G Grimbizis (G)

1st Department of Obstetrics and Gynecology, Unit for Human Reproduction, Papageorgiou General Hospital, Medical School, Aristotle University of Thessaloniki, Efkarpia, 56403, Thessaloniki, Greece.

E M Kolibianakis (EM)

1st Department of Obstetrics and Gynecology, Unit for Human Reproduction, Papageorgiou General Hospital, Medical School, Aristotle University of Thessaloniki, Efkarpia, 56403, Thessaloniki, Greece.

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