Transcriptional activity of vitamin D receptor in human periodontal ligament cells is diminished under inflammatory conditions.

Cholecalciferol / pharmacology Humans Periodontal Ligament Porphyromonas gingivalis Receptors, Calcitriol Vitamin D
VDR inflammation mesenchymal stem cells periodontal ligament vitamin D

Journal

Journal of periodontology
ISSN: 1943-3670
Titre abrégé: J Periodontol
Pays: United States
ID NLM: 8000345

Informations de publication

Date de publication:
01 2021
Historique:
received: 18 09 2019
revised: 22 12 2019
accepted: 26 04 2020
pubmed: 1 6 2020
medline: 20 4 2021
entrez: 1 6 2020
Statut: ppublish

Résumé

Although vitamin D Cells isolated from six different donors were treated with either 1,25(OH) The vitamin D This study indicates that the transcriptional activity of VDR is diminished under inflammatory conditions, which might mitigate the effectiveness of vitamin D

Sections du résumé

BACKGROUND
Although vitamin D
METHODS
Cells isolated from six different donors were treated with either 1,25(OH)
RESULTS
The vitamin D
CONCLUSIONS
This study indicates that the transcriptional activity of VDR is diminished under inflammatory conditions, which might mitigate the effectiveness of vitamin D

Identifiants

DOI: 10.1002/JPER.19-0541 PMID: 32474936 PMC: PMC7891446
pubmed: 32474936
doi: 10.1002/JPER.19-0541
pmc: PMC7891446
doi:

Substances chimiques

Receptors, Calcitriol 0
VDR protein, human 0
Vitamin D 1406-16-2
Cholecalciferol 1C6V77QF41

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

137-148

Informations de copyright

© 2020 The Authors. Journal of Periodontology published by Wiley Periodicals LLC on behalf of American Academy of Periodontology.

Références

Periodontol 2000. 2001;25:8-20
pubmed: 11155179
J Clin Periodontol. 2016 Jan;43(1):72-84
pubmed: 26719165
Hypertension. 2016 Dec;68(6):1424-1431
pubmed: 27777363
Periodontol 2000. 2015 Oct;69(1):255-73
pubmed: 26252412
Sci Rep. 2017 Nov 17;7(1):15789
pubmed: 29150625
N Engl J Med. 2007 Jul 19;357(3):266-81
pubmed: 17634462
Adolesc Health Med Ther. 2010 Jan 26;1:1-8
pubmed: 28028383
PLoS One. 2014 Feb 28;9(2):e90301
pubmed: 24587317
J Periodontol. 2014 Oct;85(10):1321-32
pubmed: 24794688
Chem Biol. 2014 Mar 20;21(3):319-29
pubmed: 24529992
Prog Biophys Mol Biol. 2006 Sep;92(1):4-8
pubmed: 16563471
PLoS One. 2012;7(6):e39878
pubmed: 22761920
Curr Opin Clin Nutr Metab Care. 2012 Nov;15(6):567-79
pubmed: 23075936
Mediators Inflamm. 2019 Apr 23;2019:8127301
pubmed: 31178663
J Periodontol. 2021 Jan;92(1):137-148
pubmed: 32474936
J Clin Endocrinol Metab. 2015 Jun;100(6):2425-33
pubmed: 25856210
J Biol Chem. 2005 Dec 9;280(49):40589-98
pubmed: 16195230
J Bone Miner Res. 2016 Jan;31(1):52-64
pubmed: 26179215
Steroids. 2001 Mar-May;66(3-5):399-408
pubmed: 11179749
Am J Clin Nutr. 2004 Dec;80(6 Suppl):1678S-88S
pubmed: 15585788
J Dent Res. 2011 Aug;90(8):1007-12
pubmed: 21555774
Periodontol 2000. 2013 Oct;63(1):198-216
pubmed: 23931061
J Periodontal Res. 2018 Feb;53(1):98-106
pubmed: 28872184
J Periodontol. 2018 Mar;89(3):294-302
pubmed: 29520786
J Immunol. 2014 Sep 1;193(5):2538-45
pubmed: 25057006
Sci Rep. 2017 Oct 9;7(1):12856
pubmed: 28993635
Cell Immunol. 2004 Nov-Dec;232(1-2):137-43
pubmed: 15876428
Sci Rep. 2017 Feb 17;7:42816
pubmed: 28211493
Front Biosci. 2005 Jan 01;10:119-34
pubmed: 15574355
Ann Epidemiol. 2009 Feb;19(2):73-8
pubmed: 18329892
J Periodontal Res. 2006 Aug;41(4):303-10
pubmed: 16827724
Arch Oral Biol. 2009 Jul;54(7):625-33
pubmed: 19464673
Gynecol Endocrinol. 2007 Jan;23(1):13-24
pubmed: 17484507
Mol Endocrinol. 2003 Nov;17(11):2320-8
pubmed: 12893883
J Biol Chem. 1990 Dec 15;265(35):21881-8
pubmed: 2174889
Cytotherapy. 2006;8(4):315-7
pubmed: 16923606
Kaohsiung J Med Sci. 2007 Jan;23(1):1-7
pubmed: 17282979
J Periodontal Res. 2014 Oct;49(5):545-53
pubmed: 24256576
J Biol Chem. 2013 Jul 5;288(27):19450-8
pubmed: 23671281
Periodontol 2000. 2005;39:91-117
pubmed: 16135066
Arch Oral Biol. 2013 Apr;58(4):397-407
pubmed: 23083515
J Periodontal Res. 2018 Aug;53(4):589-597
pubmed: 29582430
J Indian Soc Periodontol. 2013 May;17(3):302-8
pubmed: 24049329
J Periodontal Res. 2015 Oct;50(5):666-73
pubmed: 25495336
J Inflamm Res. 2014 May 29;7:69-87
pubmed: 24971027
Int J Dent. 2018 Oct 1;2018:7315797
pubmed: 30364037
Gut. 2004 Aug;53(8):1129-36
pubmed: 15247180
PLoS One. 2012;7(12):e52053
pubmed: 23251684
Steroids. 2004 Apr;69(4):219-26
pubmed: 15183687
Front Immunol. 2019 Jul 18;10:1664
pubmed: 31379856
J Periodontol. 2011 Jan;82(1):25-32
pubmed: 20809866

Auteurs

Alice Blufstein (A)

Department of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria.

Christian Behm (C)

Department of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria.

Barbara Kubin (B)

Department of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria.

Johannes Gahn (J)

Department of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria.

Andreas Moritz (A)

Department of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria.

Xiaohui Rausch-Fan (X)

Department of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria.

Oleh Andrukhov (O)

Department of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Lipides › Lipides membranaires › Stérols › Cholécalciférol › Transcriptional activity of vitamin D receptor...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Transcriptional activity of vitamin D receptor...
questionsmedicales.fr › Système stomatognathique › Bouche › Denture › Parodonte › Desmodonte › Transcriptional activity of vitamin D receptor...
questionsmedicales.fr › Bactéries › Bactéries à Gram négatif › Bactéries anaérobies à Gram négatif › Bâtonnets à Gram négatif anaérobies droits, incurvés et spiralés › Bacteroidaceae › Porphyromonas › Porphyromonas gingivalis › Transcriptional activity of vitamin D receptor...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Récepteurs cytoplasmiques et nucléaires › Récepteur calcitriol › Transcriptional activity of vitamin D receptor...
questionsmedicales.fr › Composés polycycliques › Composés à cycles fusionnés › Stéroïdes › Sécostéroïdes › Vitamine D › Transcriptional activity of vitamin D receptor...