A rare case of pelvic primitive neuroectodermal tumor with misleading symptoms: A case report.

Case report ES, Ewing Sarcoma PNET, Primitive NeuroEctodermal Tumors Primitive neuroectodermal tumors Surgical oncology pPNET, Peripheral Primitive NeuroEctodermal Tumors

Journal

Annals of medicine and surgery (2012)
ISSN: 2049-0801
Titre abrégé: Ann Med Surg (Lond)
Pays: England
ID NLM: 101616869

Informations de publication

Date de publication:
Jul 2020
Historique:
received: 24 01 2020
revised: 04 05 2020
accepted: 07 05 2020
entrez: 2 6 2020
pubmed: 2 6 2020
medline: 2 6 2020
Statut: epublish

Résumé

Peripheral Primitive NeuroEctodermal Tumors (pPNETs) are rare highly malignant tumors; originating from the neuroectoderm. Although PNETs may arise in various locations (most commonly in the extremities), very few cases have been reported in the pelvis. There is still poor evidence about the management of these tumors in the literature. We present a rare case of pelvic PNET in a 20-year-old male. The patient presented with symptoms mimicking a lumbar disk hernia, which delayed the diagnosis. He was managed with a combination of a debulking procedure, adjuvant chemotherapy, radiotherapy; and has been in remission for 2 years upon follow-up. This case highlights the importance of diagnosing such aggressive tumors as early as possible (as prognosis may vary significantly), and the challenge in the management of PNETs due to poor evidence.

Identifiants

pubmed: 32477503
doi: 10.1016/j.amsu.2020.05.010
pii: S2049-0801(20)30098-4
pmc: PMC7251491
doi:

Types de publication

Case Reports

Langues

eng

Pagination

93-96

Informations de copyright

© 2020 The Author(s).

Déclaration de conflit d'intérêts

The authors declare that there is no conflict of interest.

Références

Cancer Treat Res. 1997;92:253-308
pubmed: 9494764
Gynecol Oncol. 2003 Oct;91(1):247-53
pubmed: 14529689
Ann Otol Rhinol Laryngol. 1996 Oct;105(10):838-43
pubmed: 8865780
Pediatr Clin North Am. 1997 Aug;44(4):991-1004
pubmed: 9286296
Int J Surg. 2018 Dec;60:132-136
pubmed: 30342279
Clin Radiol. 2001 Mar;56(3):206-15
pubmed: 11247698
Eur J Cancer. 1997 Dec;33(14):2360-7
pubmed: 9616282
Iran J Med Sci. 2014 Jan;39(1):71-4
pubmed: 24453398
Oncotarget. 2014 Dec 30;5(24):12968-77
pubmed: 25587032
Neurol Med Chir (Tokyo). 2008 Feb;48(2):72-6
pubmed: 18296876
Pediatr Pathol. 1989;9(4):387-407
pubmed: 2798266

Auteurs

Kusay Ayoub (K)

Department of Surgery, Aleppo University Hospital, University of Aleppo, Syria.

Ammar Niazi (A)

Department of Surgery, Aleppo University Hospital, University of Aleppo, Syria.

Baraa Shebli (B)

Faculty of Medicine, University of Aleppo, Syria.

Rand Batal (R)

Faculty of Medicine, University of Aleppo, Syria.

Hamed Kozom (H)

Faculty of Medicine, University of Aleppo, Syria.

Lina Ghabreau (L)

Department of Pathology, Aleppo University Hospital, University of Aleppo, Syria.

Nihad Mahli (N)

Department of Surgery, Aleppo University Hospital, University of Aleppo, Syria.

Classifications MeSH