Comparative Analysis and Evaluation of State-of-the-Art Medication Mapping Tools to Transform a Local Medication Terminology to RxNorm.


Journal

AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
ISSN: 2153-4063
Titre abrégé: AMIA Jt Summits Transl Sci Proc
Pays: United States
ID NLM: 101539486

Informations de publication

Date de publication:
2020
Historique:
entrez: 2 6 2020
pubmed: 2 6 2020
medline: 2 6 2020
Statut: epublish

Résumé

Mapping local terminologies to standardized terminologies facilitates secondary use of electronic health records (EHR). Penn Medicine comprises multiple hospitals and facilities within the Philadelphia Metropolitan area providing services from primary to quaternary care. Our Penn Medicine (PennMed) data include medications collected during both inpatient and outpatient encounters at multiple facilities. Our goal was to map 941,198 unique medication terms to RxNorm, a standardized drug nomenclature from the National Library of Medicine (NLM). We chose three popular tools for mapping: NLM's RxMix and RxNav-in-a-Box, OHDSI's Usagi and Mayo Clinic's MedXN. We manually reviewed 400 mappings obtained from each tool and evaluated their performance for drug name, strength, form, and route. RxMix performed the best with an F1 score of 90% for drug name versus Usagi's 82% and MedXN's 74%. We discuss the strengths and limitations of each method and tips for other institutions seeking to map a local terminology to RxNorm.

Identifiants

pubmed: 32477631
pmc: PMC7233099

Types de publication

Journal Article

Langues

eng

Pagination

126-135

Informations de copyright

©2020 AMIA - All rights reserved.

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Auteurs

Lena Davidson (L)

Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania.
Institute for Biomedical Informatics, University of Pennsylvania.
Center for Excellence in Environmental Toxicology, University of Pennsylvania.
Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia.

Mary Regina Boland (MR)

Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania.
Institute for Biomedical Informatics, University of Pennsylvania.
Center for Excellence in Environmental Toxicology, University of Pennsylvania.
Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia.

Classifications MeSH