Economic Process Evaluation and Environmental Life-Cycle Assessment of Bio-Aromatics Production.
aromatics
fermentation
life-cycle assessment
pHBA
process development
Journal
Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513
Informations de publication
Date de publication:
2020
2020
Historique:
received:
08
11
2019
accepted:
09
04
2020
entrez:
2
6
2020
pubmed:
2
6
2020
medline:
2
6
2020
Statut:
epublish
Résumé
The bio-based production of aromatics is experiencing a renaissance with systems and synthetic biology approaches promising to deliver bio-catalysts that will reach yields, rates, and titers comparable to already existing bulk bio-processes for the production of amino acids for instance. However, aromatic building blocks derived from petrochemical routes have a huge economic advantage, they are cheap, and very cheap in fact. In this article, we are trying to shed light on an important aspect of biocatalyst development that is frequently overlooked when working on strain development: economic and environmental impact of the production process. We estimate the production cost and environmental impact of a microbial fermentation process depending on culture pH, carbon source and process scale. As a model molecule we use
Identifiants
pubmed: 32478047
doi: 10.3389/fbioe.2020.00403
pmc: PMC7237583
doi:
Types de publication
Journal Article
Langues
eng
Pagination
403Informations de copyright
Copyright © 2020 Krömer, Ferreira, Petrides and Kohlheb.
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