Vitamin D and stress urinary incontinence in pregnancy: a cross-sectional study.
25-hydroxy vitamin D
pregnancy
stress urinary incontinence
urinary incontinence
vitamin D insufficiency
Journal
BJOG : an international journal of obstetrics and gynaecology
ISSN: 1471-0528
Titre abrégé: BJOG
Pays: England
ID NLM: 100935741
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
accepted:
19
05
2020
pubmed:
2
6
2020
medline:
15
12
2020
entrez:
2
6
2020
Statut:
ppublish
Résumé
To assess the association between levels of vitamin D and urinary incontinence (UI) in pregnancy. A cross-sectional study. Secondary analysis of a randomised controlled trial. Two university hospitals in Norway. A total of 851 healthy, pregnant women >18 years in gestational weeks 18-22 with a singleton live fetus. Data on UI were collected from a questionnaire at inclusion and serum analysis of 25-hydroxy vitamin D (25(OH)D) was performed. Univariable and multivariable logistic regression analyses were applied to study associations between exposure and outcomes. Prevalence of self-reported UI, stress (SUI) and urge (UUI) or mixed UI. In total, 230/851 (27%) of the participants were vitamin D insufficient (25(OH)D <50 nmol/l) and 42% reported to have any UI. Women with 25(OH)D <50 nmol/l were more likely to report any UI (P = 0.03) and SUI (P < 0.01) compared with women with 25(OH)D ≥50 nmol/l. In a univariable logistic regression analysis, serum levels of 25(OH)D <50 nmol/l was associated with increased risk of any UI (odds ratio [OR] 1.5 with 95% CI 1.0-2.1), SUI only (OR 1.7, 95% CI 1.2-2.4), but not mixed UI or UUI only (OR 0.8, 95% CI 0.5-1.5). In a multivariable logistic regression model, serum levels of 25(OH)D <50 nmol/l were associated with a higher risk of experiencing SUI only (OR 1.5, 95% CI 1.1-2.2). Serum 25(OH)D <50 nmol/l was associated with increased risk of any UI, and SUI in particular. Low levels of vitamin D are associated with increased risk of urinary incontinence in pregnancy.
Identifiants
pubmed: 32479701
doi: 10.1111/1471-0528.16340
doi:
Substances chimiques
Vitamin D
1406-16-2
25-hydroxyvitamin D
A288AR3C9H
Types de publication
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1704-1711Subventions
Organisme : Norwegian Fund for Postgraduate Training in Physiotherapy
ID : 7/370-00/05
Pays : International
Organisme : The Liaison Committee for Central Norway Regional Health Authority and the Norwegian University of Science and Technology
ID : 2006/9264-95
Pays : International
Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
© 2020 The Authors. BJOG: An International Journal of Obstetrics and Gynaecology published by John Wiley & Sons Ltd on behalf of Royal College of Obstetricians and Gynaecologists.
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