SARS-CoV-2 antibody testing-questions to be asked.
Antibody response
COVID-19
diagnostic pathway
external quality assurance
immunity
immunoassay
neutralization assay
respiratory tract infections
serologic tests
severe acute respiratory syndrome coronavirus 2
Journal
The Journal of allergy and clinical immunology
ISSN: 1097-6825
Titre abrégé: J Allergy Clin Immunol
Pays: United States
ID NLM: 1275002
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
30
04
2020
revised:
18
05
2020
accepted:
25
05
2020
pubmed:
2
6
2020
medline:
17
7
2020
entrez:
2
6
2020
Statut:
ppublish
Résumé
Severe acute respiratory syndrome coronavirus 2 infection and development of coronavirus disease 2019 presents a major health care challenge of global dimensions. Laboratory diagnostics of infected patients, and the assessment of immunity against severe acute respiratory syndrome coronavirus 2, presents a major cornerstone in handling the pandemic. Currently, there is an increase in demand for antibody testing and a large number of tests are already marketed or are in the late stage of development. However, the interpretation of test results depends on many variables and factors, including sensitivity, specificity, potential cross-reactivity and cross-protectivity, the diagnostic value of antibodies of different isotypes, and the use of antibody testing in identification of acutely ill patients or in epidemiological settings. In this article, the recently established COVID-19 Task Force of the German Society for Clinical Chemistry and Laboratory Medicine (DGKL) addresses these issues on the basis of currently available data sets in this rapidly moving field.
Identifiants
pubmed: 32479758
pii: S0091-6749(20)30739-9
doi: 10.1016/j.jaci.2020.05.020
pmc: PMC7256507
pii:
doi:
Substances chimiques
Antibodies, Viral
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
35-43Informations de copyright
Copyright © 2020 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.
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