Biochemical, electrophysiological and immunological characterization of the venom from Centruroides baergi, a new scorpion species of medical importance in Mexico.
Centruroides baergi
Human scFvs
Scorpion β-toxins
Sodium channels
Venom neutralization
Journal
Toxicon : official journal of the International Society on Toxinology
ISSN: 1879-3150
Titre abrégé: Toxicon
Pays: England
ID NLM: 1307333
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
23
03
2020
revised:
14
05
2020
accepted:
25
05
2020
pubmed:
2
6
2020
medline:
28
8
2020
entrez:
2
6
2020
Statut:
ppublish
Résumé
In this communication the isolation, chemical and physiological characterization of three new toxins from the scorpion Centruroides baergi are reported. Their immunoreactive properties with scFvs generated in our group are described. The three new peptides, named Cb1, Cb2 and Cb3 affect voltage-dependent Na
Identifiants
pubmed: 32479835
pii: S0041-0101(20)30252-X
doi: 10.1016/j.toxicon.2020.05.021
pii:
doi:
Substances chimiques
Recombinant Proteins
0
Scorpion Venoms
0
Single-Chain Antibodies
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
10-18Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.