Usefulness of Platelet-to-Lymphocyte Ratio as a Marker of Sarcopenia for Critical Limb Threatening Ischemia.


Journal

Annals of vascular surgery
ISSN: 1615-5947
Titre abrégé: Ann Vasc Surg
Pays: Netherlands
ID NLM: 8703941

Informations de publication

Date de publication:
Apr 2021
Historique:
received: 15 04 2020
revised: 16 05 2020
accepted: 21 05 2020
pubmed: 2 6 2020
medline: 3 8 2021
entrez: 2 6 2020
Statut: ppublish

Résumé

Sarcopenia is a factor of poor prognosis for patients with critical limb threatening ischemia (CLTI), but its diagnosis requires imaging measurements and is time consuming. We investigated whether preoperative platelet-to-lymphocyte ratio (PLR) could be an easy and rapid marker of sarcopenia. Patients treated for CLTI between January 2019 and July 2019 were included in this single-center retrospective study. Sarcopenia was defined by a psoas muscle index (PMI) <5.5 cm Sixty-four patients were included in the study: 48 nonsarcopenic patients (mean PMI 7.34 cm PLR might help identifying a subgroup of CTLI patients associated with poor prognosis but does not seem appropriate to be used as a marker of sarcopenia given its low sensitivity.

Sections du résumé

BACKGROUND BACKGROUND
Sarcopenia is a factor of poor prognosis for patients with critical limb threatening ischemia (CLTI), but its diagnosis requires imaging measurements and is time consuming. We investigated whether preoperative platelet-to-lymphocyte ratio (PLR) could be an easy and rapid marker of sarcopenia.
METHODS METHODS
Patients treated for CLTI between January 2019 and July 2019 were included in this single-center retrospective study. Sarcopenia was defined by a psoas muscle index (PMI) <5.5 cm
RESULTS RESULTS
Sixty-four patients were included in the study: 48 nonsarcopenic patients (mean PMI 7.34 cm
CONCLUSIONS CONCLUSIONS
PLR might help identifying a subgroup of CTLI patients associated with poor prognosis but does not seem appropriate to be used as a marker of sarcopenia given its low sensitivity.

Identifiants

pubmed: 32479878
pii: S0890-5096(20)30434-9
doi: 10.1016/j.avsg.2020.05.027
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

72-78

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Auteurs

Mégane Pizzimenti (M)

FMTS, Department of Physiology, EA3072 Mitochondria, Oxidative Stress and Muscular Protection, University of Strasbourg, Strasbourg, France; Department of Physiology and Functional Explorations, University Hospital of Strasbourg, Strasbourg, France.

Anne L Charles (AL)

Department of Physiology and Functional Explorations, University Hospital of Strasbourg, Strasbourg, France.

Marianne Riou (M)

FMTS, Department of Physiology, EA3072 Mitochondria, Oxidative Stress and Muscular Protection, University of Strasbourg, Strasbourg, France.

Fabien Thaveau (F)

Department of Physiology and Functional Explorations, University Hospital of Strasbourg, Strasbourg, France; Department of Vascular Surgery and Kidney Transplantation, University Hospital of Strasbourg, Strasbourg, France.

Nabil Chakfé (N)

Department of Physiology and Functional Explorations, University Hospital of Strasbourg, Strasbourg, France; Department of Vascular Surgery and Kidney Transplantation, University Hospital of Strasbourg, Strasbourg, France.

Bernard Geny (B)

FMTS, Department of Physiology, EA3072 Mitochondria, Oxidative Stress and Muscular Protection, University of Strasbourg, Strasbourg, France; Department of Physiology and Functional Explorations, University Hospital of Strasbourg, Strasbourg, France.

Anne Lejay (A)

FMTS, Department of Physiology, EA3072 Mitochondria, Oxidative Stress and Muscular Protection, University of Strasbourg, Strasbourg, France; Department of Physiology and Functional Explorations, University Hospital of Strasbourg, Strasbourg, France; Department of Vascular Surgery and Kidney Transplantation, University Hospital of Strasbourg, Strasbourg, France. Electronic address: anne.lejay@chru-strasbourg.fr.

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