Mining the jewels of the cortex's crowning mystery.

Axons Interneurons Neurons Pyramidal Cells

Journal

Current opinion in neurobiology
ISSN: 1873-6882
Titre abrégé: Curr Opin Neurobiol
Pays: England
ID NLM: 9111376

Informations de publication

Date de publication:
08 2020
Historique:
received: 03 12 2019
revised: 30 03 2020
accepted: 13 04 2020
pubmed: 2 6 2020
medline: 11 11 2020
entrez: 2 6 2020
Statut: ppublish

Résumé

Neocortical Layer 1 consists of a dense mesh of excitatory and inhibitory axons, dendrites of pyramidal neurons, as well as neuromodulatory inputs from diverse brain regions. Layer 1 also consists of a sparse population of inhibitory interneurons, which are appropriately positioned to receive and integrate the information from these regions of the brain and modulate cortical processing. Despite being among the sparsest neuronal population in the cortex, Layer 1 interneurons perform powerful computations and have elaborate morphologies. Here we review recent studies characterizing their origin, morphology, physiology, and molecular profiles, as well as their connectivity and in vivo response properties.

Identifiants

DOI: 10.1016/j.conb.2020.04.005 PMID: 32480351 PMC: PMC8075042
pubmed: 32480351
pii: S0959-4388(20)30084-2
doi: 10.1016/j.conb.2020.04.005
pmc: PMC8075042
mid: NIHMS1646864
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

154-161

Subventions

Organisme : NINDS NIH HHS
ID : P01 NS074972
Pays : United States
Organisme : NIMH NIH HHS
ID : UG3 MH120096
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS110079
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH071679
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS081297
Pays : United States

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Références

Neuron. 2016 Mar 2;89(5):1031-45
pubmed: 26898778
J Neurosci. 2004 Nov 3;24(44):9878-87
pubmed: 15525772
Neuron. 2017 Dec 6;96(5):1204
pubmed: 29216453
Front Neuroanat. 2014 Jan 16;7:52
pubmed: 24474905
Nat Neurosci. 2016 Feb;19(2):335-46
pubmed: 26727548
J Neurosci. 2004 Mar 3;24(9):2286-95
pubmed: 14999079
Annu Rev Neurosci. 1982;5:363-70
pubmed: 7041779
Elife. 2018 Mar 20;7:
pubmed: 29557780
J Neurosci. 2004 Feb 11;24(6):1272-9
pubmed: 14960597
Development. 2002 Jul;129(14):3479-92
pubmed: 12091317
J Neurosci. 2005 Aug 3;25(31):7268-77
pubmed: 16079409
Dev Biol. 2005 Jan 15;277(2):332-46
pubmed: 15617678
Neuron. 2018 Nov 7;100(3):684-699.e6
pubmed: 30269988
Science. 2015 Nov 27;350(6264):aac9462
pubmed: 26612957
Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7123-8
pubmed: 12773624
J Neurosci. 2011 Nov 16;31(46):16570-80
pubmed: 22090484
J Neurosci. 1996 Sep 1;16(17):5290-300
pubmed: 8757242
J Neurosci. 2004 Mar 17;24(11):2612-22
pubmed: 15028753
Nat Neurosci. 2018 Feb;21(2):218-227
pubmed: 29358666
Nat Rev Neurosci. 2003 Jun;4(6):496-505
pubmed: 12778121
Nat Neurosci. 2016 Feb;19(2):299-307
pubmed: 26691828
Neuron. 2005 Nov 23;48(4):591-604
pubmed: 16301176
J Neurosci. 2015 Sep 16;35(37):12869-89
pubmed: 26377473
Cereb Cortex. 2011 Apr;21(4):845-52
pubmed: 20732898
Cereb Cortex. 2011 Aug;21(8):1818-26
pubmed: 21220765
J Comp Neurol. 2007 Jan 20;500(3):419-32
pubmed: 17120279
Nat Neurosci. 2013 Feb;16(2):210-8
pubmed: 23313910
Nature. 2018 Mar 22;555(7697):457-462
pubmed: 29513653
Dev Neurobiol. 2011 Jan 1;71(1):45-61
pubmed: 21154909
Nature. 2000 Mar 2;404(6773):99-103
pubmed: 10716451
J Neurosci. 2019 Jan 2;39(1):125-139
pubmed: 30413647
Nat Neurosci. 2005 Aug;8(8):1002-12
pubmed: 16041369
J Neurosci. 2010 Feb 3;30(5):1582-94
pubmed: 20130169
Nat Neurosci. 1999 Jan;2(1):79-87
pubmed: 10195184
Nature. 2011 Dec 07;480(7377):331-5
pubmed: 22158104
J Neurophysiol. 2019 Jun 1;121(6):2202-2214
pubmed: 30969800
Cereb Cortex. 2015 Aug;25(8):2114-26
pubmed: 24554728
Science. 2012 Feb 24;335(6071):989-93
pubmed: 22363012
Nature. 2009 Oct 29;461(7268):1278-81
pubmed: 19865171
Cereb Cortex. 1997 Sep;7(6):476-86
pubmed: 9276173
J Neurosci. 2002 Jun 15;22(12):4973-86
pubmed: 12077194
Cereb Cortex. 2016 Jun;26(6):2612-25
pubmed: 25979090
Cereb Cortex. 2012 Sep;22(9):2120-30
pubmed: 22021915
Neuron. 2001 Feb;29(2):353-66
pubmed: 11239428
J Comp Neurol. 2019 Dec 1;527(17):2860-2874
pubmed: 31070778
Nature. 2014 Mar 20;507(7492):358-61
pubmed: 24572358
J Neurosci. 2010 Dec 15;30(50):16796-808
pubmed: 21159951
Development. 2016 May 15;143(10):1753-65
pubmed: 27034423
PLoS One. 2013 Oct 14;8(10):e77339
pubmed: 24155945
Front Syst Neurosci. 2013 Jan 09;6:79
pubmed: 23316142
J Neurosci. 2019 Dec 11;39(50):10060-10070
pubmed: 31685651
Neuron. 2012 Feb 23;73(4):814-28
pubmed: 22365553
J Neurosci. 2008 Dec 10;28(50):13582-91
pubmed: 19074032
J Neurosci. 2012 Dec 5;32(49):17813-23
pubmed: 23223300

Auteurs

Leena A Ibrahim (LA)

Department of Neurobiology, Harvard Medical School, 220 Longwood Ave., Boston, MA 02115, USA. Electronic address: leena.ali@hms.harvard.edu.

Ben Schuman (B)

NYU Neuroscience Institute and the Department of Neuroscience and Physiology, NYU Neuroscience Institute, New York University School of Medicine, 522 First Avenue, New York, NY 10016, USA.

Rachel Bandler (R)

Stanley Center at the Broad, 75 Ames St., Cambridge, MA 02142, USA.

Bernardo Rudy (B)

NYU Neuroscience Institute and the Department of Neuroscience and Physiology, NYU Neuroscience Institute, New York University School of Medicine, 522 First Avenue, New York, NY 10016, USA. Electronic address: Bernardo.Rudy@nyulangone.org.

Gord Fishell (G)

Department of Neurobiology, Harvard Medical School, 220 Longwood Ave., Boston, MA 02115, USA; Stanley Center at the Broad, 75 Ames St., Cambridge, MA 02142, USA. Electronic address: gordon_fishell@hms.harvard.edu.

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Classifications MeSH

questionsmedicales.fr › Cellules › Neurones › Neurofibres › Axones › Mining the jewels of the cortex's crowning mystery.
questionsmedicales.fr › Cellules › Neurones › Interneurones › Mining the jewels of the cortex's crowning mystery.
questionsmedicales.fr › Cellules › Neurones › Mining the jewels of the cortex's crowning mystery.
questionsmedicales.fr › Cellules › Neurones › Cellules pyramidales › Mining the jewels of the cortex's crowning mystery.