Hallmarks of Splicing Defects in Cancer: Clinical Applications in the Era of Personalized Medicine.
RNA processing
cancer therapies
oncogenesis
spliceosome
splicing
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
28 May 2020
28 May 2020
Historique:
received:
24
04
2020
revised:
25
05
2020
accepted:
25
05
2020
entrez:
3
6
2020
pubmed:
3
6
2020
medline:
3
6
2020
Statut:
epublish
Résumé
Alternative splicing promotes proteome diversity by using limited number of genes, a key control point of gene expression. Splicing is carried out by large macromolecular machineries, called spliceosome, composed of small RNAs and proteins. Alternative splicing is regulated by splicing regulatory
Identifiants
pubmed: 32481522
pii: cancers12061381
doi: 10.3390/cancers12061381
pmc: PMC7352608
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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