Self-reported Use of K2/Spice for Appetite Stimulation: A Case Report.
appetite
appetite stimulation
cb-1
k2/spice
synthetic cannabinoids
synthetic cannabis
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
27 Apr 2020
27 Apr 2020
Historique:
entrez:
3
6
2020
pubmed:
3
6
2020
medline:
3
6
2020
Statut:
epublish
Résumé
This case report explores the use of K2/Spice (synthetic cannabinoids) in a patient as an appetite stimulant. The effects of synthetic cannabinoids range widely but are more commonly known to suppress appetite in the cannabinoid-naive. Our patient was not cannabinoid- naive and had used cannabis before. Rat models have demonstrated results similar to those in this patient, who had prior tetrahydrocannabinol (THC) exposure resulting in appetite stimulation rather than suppression when exposed to a synthetic cannabinoid. This is likely explained by other rat models that have shown long-term use of cannabis resulting in receptor downregulation of cannabinoid receptor type 1 (CB-1).
Identifiants
pubmed: 32483510
doi: 10.7759/cureus.7860
pmc: PMC7255079
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e7860Informations de copyright
Copyright © 2020, Torres et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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