A novel cohorting and isolation strategy for suspected COVID-19 cases during a pandemic.


Journal

The Journal of hospital infection
ISSN: 1532-2939
Titre abrégé: J Hosp Infect
Pays: England
ID NLM: 8007166

Informations de publication

Date de publication:
Aug 2020
Historique:
received: 05 05 2020
accepted: 26 05 2020
pubmed: 3 6 2020
medline: 22 8 2020
entrez: 3 6 2020
Statut: ppublish

Résumé

The COVID-19 pandemic presents a significant infection prevention and control challenge. The admission of large numbers of patients with suspected COVID-19 disease risks overwhelming the capacity to protect other patients from exposure. The delay between clinical suspicion and confirmatory testing adds to the complexity of the problem. We implemented a triage tool aimed at minimizing hospital-acquired COVID-19 particularly in patients at risk of severe disease. Patients were allocated to triage categories defined by likelihood of COVID-19 and risk of a poor outcome. Category A (low-likelihood; high-risk), B (high-likelihood; high-risk), C (high-likelihood; low-risk) and D (low-likelihood; low-risk). This determined the order of priority for isolation in single-occupancy rooms with Category A the highest. Patients in other groups were cohorted when isolation capacity was limited with additional interventions to reduce transmission. Ninety-three patients were evaluated with 79 (85%) receiving a COVID-19 diagnosis during their admission. Of those without a COVID-19 diagnosis: 10 were initially triaged to Category A; 0 to B; 1 to C and 4 to D. All high-risk patients requiring isolation were, therefore, admitted to single-occupancy rooms and protected from exposure. Twenty-eight (30%) suspected COVID-19 patients were evaluated to be low risk (groups C and D) and eligible for cohorting. No symptomatic hospital-acquired infections were detected in the cohorted patients. Application of a clinical triage tool to guide isolation and cohorting decisions may reduce the risk of hospital-acquired transmission of COVID-19 especially to individuals at the greatest of risk of severe disease.

Sections du résumé

BACKGROUND BACKGROUND
The COVID-19 pandemic presents a significant infection prevention and control challenge. The admission of large numbers of patients with suspected COVID-19 disease risks overwhelming the capacity to protect other patients from exposure. The delay between clinical suspicion and confirmatory testing adds to the complexity of the problem.
METHODS METHODS
We implemented a triage tool aimed at minimizing hospital-acquired COVID-19 particularly in patients at risk of severe disease. Patients were allocated to triage categories defined by likelihood of COVID-19 and risk of a poor outcome. Category A (low-likelihood; high-risk), B (high-likelihood; high-risk), C (high-likelihood; low-risk) and D (low-likelihood; low-risk). This determined the order of priority for isolation in single-occupancy rooms with Category A the highest. Patients in other groups were cohorted when isolation capacity was limited with additional interventions to reduce transmission.
RESULTS RESULTS
Ninety-three patients were evaluated with 79 (85%) receiving a COVID-19 diagnosis during their admission. Of those without a COVID-19 diagnosis: 10 were initially triaged to Category A; 0 to B; 1 to C and 4 to D. All high-risk patients requiring isolation were, therefore, admitted to single-occupancy rooms and protected from exposure. Twenty-eight (30%) suspected COVID-19 patients were evaluated to be low risk (groups C and D) and eligible for cohorting. No symptomatic hospital-acquired infections were detected in the cohorted patients.
DISCUSSION CONCLUSIONS
Application of a clinical triage tool to guide isolation and cohorting decisions may reduce the risk of hospital-acquired transmission of COVID-19 especially to individuals at the greatest of risk of severe disease.

Identifiants

pubmed: 32485197
pii: S0195-6701(20)30275-9
doi: 10.1016/j.jhin.2020.05.035
pmc: PMC7261079
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

632-637

Informations de copyright

Copyright © 2020 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Références

CMAJ. 2005 Aug 30;173(5):489-95
pubmed: 16129869
N Engl J Med. 2020 Apr 30;382(18):1708-1720
pubmed: 32109013
Nat Med. 2020 May;26(5):672-675
pubmed: 32296168

Auteurs

B Patterson (B)

Department of Clinical Microbiology, University College London, London, UK. Electronic address: b.patterson1@nhs.net.

M Marks (M)

Hospital for Tropical Diseases, University College London, London, UK; Clinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.

G Martinez-Garcia (G)

Division of Infection, University College London, London, UK.

G Bidwell (G)

Hospital for Tropical Diseases, University College London, London, UK.

A Luintel (A)

Hospital for Tropical Diseases, University College London, London, UK.

D Ludwig (D)

Department of Acute Medicine, University College London, London, UK.

T Parks (T)

Hospital for Tropical Diseases, University College London, London, UK.

P Gothard (P)

Hospital for Tropical Diseases, University College London, London, UK.

R Thomas (R)

Intensive Care Department, University College London, London, UK.

S Logan (S)

Hospital for Tropical Diseases, University College London, London, UK.

K Shaw (K)

Division of Infection, University College London, London, UK.

N Stone (N)

Hospital for Tropical Diseases, University College London, London, UK.

M Brown (M)

Hospital for Tropical Diseases, University College London, London, UK.

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