CD4
CD28(lo)
CD28(null)
CD4(+)CTL
CD8(+)CTL
IgG(4)-RD
apoptosis
Journal
The Journal of allergy and clinical immunology
ISSN: 1097-6825
Titre abrégé: J Allergy Clin Immunol
Pays: United States
ID NLM: 1275002
Informations de publication
Date de publication:
01 2021
01 2021
Historique:
received:
13
02
2020
revised:
08
05
2020
accepted:
18
05
2020
pubmed:
3
6
2020
medline:
27
7
2021
entrez:
3
6
2020
Statut:
ppublish
Résumé
IgG We sought to define CD4 Blood analyses were undertaken using flow cytometry, cell sorting, transcriptomic analyses at the population and single-cell levels, and next-generation sequencing for the TCR repertoire. Tissues were interrogated using multicolor immunofluorescence. Results were correlated with clinical data. We establish that among circulating CD4 CD4
Sections du résumé
BACKGROUND
IgG
OBJECTIVE
We sought to define CD4
METHODS
Blood analyses were undertaken using flow cytometry, cell sorting, transcriptomic analyses at the population and single-cell levels, and next-generation sequencing for the TCR repertoire. Tissues were interrogated using multicolor immunofluorescence. Results were correlated with clinical data.
RESULTS
We establish that among circulating CD4
CONCLUSIONS
CD4
Identifiants
pubmed: 32485263
pii: S0091-6749(20)30741-7
doi: 10.1016/j.jaci.2020.05.022
pmc: PMC7704943
mid: NIHMS1613315
pii:
doi:
Substances chimiques
Antigens, CD
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
368-382Subventions
Organisme : NIAID NIH HHS
ID : U19 AI110495
Pays : United States
Organisme : NHLBI NIH HHS
ID : K23 HL150331
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI144295
Pays : United States
Organisme : NIAID NIH HHS
ID : K08 AI113163
Pays : United States
Organisme : NIAID NIH HHS
ID : P30 AI060354
Pays : United States
Informations de copyright
Copyright © 2020 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.