Comparing nanoparticles for drug delivery: The effect of physiological dispersion media on nanoparticle properties.


Journal

Materials science & engineering. C, Materials for biological applications
ISSN: 1873-0191
Titre abrégé: Mater Sci Eng C Mater Biol Appl
Pays: Netherlands
ID NLM: 101484109

Informations de publication

Date de publication:
Aug 2020
Historique:
received: 14 12 2019
revised: 24 03 2020
accepted: 17 04 2020
entrez: 4 6 2020
pubmed: 4 6 2020
medline: 26 3 2021
Statut: ppublish

Résumé

Delivering therapeutics to disease sites is a challenge facing modern medicine. Nanoparticle delivery systems are of considerable interest to overcome this challenge, but these systems suffer from poor clinical translation. It is believed this is, in part, due to incomplete understanding of nanoparticle physico-chemical properties in vivo. To understand how nanoparticle properties could change following intravenous delivery, Au, Ag, Fe

Identifiants

pubmed: 32487401
pii: S0928-4931(19)34676-4
doi: 10.1016/j.msec.2020.110985
pii:
doi:

Substances chimiques

Culture Media 0
Drug Carriers 0
Ferric Compounds 0
Water 059QF0KO0R
titanium dioxide 15FIX9V2JP
ferric oxide 1K09F3G675
Silver 3M4G523W1G
Gold 7440-57-5
Titanium D1JT611TNE
Zinc Oxide SOI2LOH54Z

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

110985

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Aisling M Ross (AM)

BioScience and Bioengineering Research (BioSciBer), Bernal Biomaterials, Bernal Institute, University of Limerick, Limerick, Ireland; School of Engineering, University of Limerick, Limerick, Ireland.

Tadhg Kennedy (T)

Department of Chemical Sciences, University of Limerick, Limerick, Ireland.

David McNulty (D)

Paul Scherrer Institut, CH-5232 Villigen PSI, Switzerland.

Ciara I Leahy (CI)

BioScience and Bioengineering Research (BioSciBer), Bernal Biomaterials, Bernal Institute, University of Limerick, Limerick, Ireland; Health Research Institute, (HRI), University of Limerick, Limerick, Ireland; Education and Health Sciences, University of Limerick, Limerick, Ireland.

Darragh R Walsh (DR)

BioScience and Bioengineering Research (BioSciBer), Bernal Biomaterials, Bernal Institute, University of Limerick, Limerick, Ireland; School of Engineering, University of Limerick, Limerick, Ireland.

Paul Murray (P)

BioScience and Bioengineering Research (BioSciBer), Bernal Biomaterials, Bernal Institute, University of Limerick, Limerick, Ireland; Health Research Institute, (HRI), University of Limerick, Limerick, Ireland; Education and Health Sciences, University of Limerick, Limerick, Ireland.

Andreas M Grabrucker (AM)

BioScience and Bioengineering Research (BioSciBer), Bernal Biomaterials, Bernal Institute, University of Limerick, Limerick, Ireland; Health Research Institute, (HRI), University of Limerick, Limerick, Ireland; Department of Biological Sciences, University of Limerick, Limerick, Ireland.

John J E Mulvihill (JJE)

BioScience and Bioengineering Research (BioSciBer), Bernal Biomaterials, Bernal Institute, University of Limerick, Limerick, Ireland; School of Engineering, University of Limerick, Limerick, Ireland; Health Research Institute, (HRI), University of Limerick, Limerick, Ireland. Electronic address: john.mulvihill@ul.ie.

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Classifications MeSH