Interferon-γ and voriconazole combined therapy for refractory meningeal coccidioidomycosis in a patient with interferon-γ deficiency.
Coccidioidomycosis
Gamma-interferon
Meningitis
Journal
IDCases
ISSN: 2214-2509
Titre abrégé: IDCases
Pays: Netherlands
ID NLM: 101634540
Informations de publication
Date de publication:
2020
2020
Historique:
received:
15
05
2020
revised:
18
05
2020
accepted:
18
05
2020
entrez:
4
6
2020
pubmed:
4
6
2020
medline:
4
6
2020
Statut:
epublish
Résumé
Coccidioides meningitis (CM) is a challenging infection, given the limited penetration to the cerebrospinal fluid of conventional antifungals, resulting in a high risk of recurrence. We present the first case of a successfully treated persistent CM with voriconazole and adjuvant INF-γ 1b.
Identifiants
pubmed: 32489879
doi: 10.1016/j.idcr.2020.e00835
pii: S2214-2509(20)30143-8
pii: e00835
pmc: PMC7262437
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e00835Informations de copyright
© 2020 The Authors.
Déclaration de conflit d'intérêts
AD and AM have no conflicts of interest, RH is speaker for Merck® and Biofire® and consultant to Gilead®.
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