The evaluating of pregnancy-associated plasma protein-A with the likelihood of small for gestational age.
Gestational age
Plasma protein-A
Pregnancy
Journal
Obstetrics & gynecology science
ISSN: 2287-8572
Titre abrégé: Obstet Gynecol Sci
Pays: Korea (South)
ID NLM: 101602614
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
received:
30
12
2018
revised:
09
05
2019
accepted:
28
05
2019
entrez:
4
6
2020
pubmed:
4
6
2020
medline:
4
6
2020
Statut:
ppublish
Résumé
Recently, strong evidences were obtained on the association between low pregnancy-associated plasma protein-A (PAPP-A) levels in the first trimester and poor outcomes of pregnancy. This cross-sectional study was conducted on all pregnant women who were referred to the Obstetrics and Gynecology Clinic at Imam Hossein Hospital in Tehran, Iran in 2014. Women were asked to attend clinical examinations and screening at 11-14 weeks of gestation. Based on the definition, 14.5% of neonates found to be small for gestational age (SGA). There was a strong association between PAPP-A levels and birth weight. The mean PAPP-A level in the mothers of neonates who were SGA was significantly lower than those without this poor outcome. Based on the receiver operating characteristic curve analysis, serum PAPP-A level was a main determinant in the prediction of SGA neonates. The serum PAPP-A level at 11-13 weeks of gestation can effectively predict the increased risk for fetal growth retardation. In patients in this study, the best cutoff value for PAPP-A was 0.75
Identifiants
pubmed: 32489966
doi: 10.5468/ogs.2020.63.3.225
pmc: PMC7231942
doi:
Types de publication
Journal Article
Langues
eng
Pagination
225-230Informations de copyright
Copyright © 2020 Korean Society of Obstetrics and Gynecology.
Déclaration de conflit d'intérêts
Conflict of interest: No potential conflict of interest relevant to this article was reported.
Références
Ultrasound Obstet Gynecol. 2007 Feb;29(2):135-40
pubmed: 17221926
Hypertens Pregnancy. 2003;22(2):143-8
pubmed: 12908998
Ultrasound Obstet Gynecol. 2007 Feb;29(2):128-34
pubmed: 17149788
Ultrasound Obstet Gynecol. 2008 May;31(5):493-502
pubmed: 18432600
Lancet. 1998 Aug 1;352(9125):343-6
pubmed: 9717920
Prenat Diagn. 2009 Dec;29(13):1244-8
pubmed: 19862778
Prenat Diagn. 2005 Oct;25(10):949-53
pubmed: 16086443
J Obstet Gynaecol India. 2017 Aug;67(4):247-252
pubmed: 28706362
Prenat Diagn. 2010 Jun;30(6):503-8
pubmed: 20509148
Am J Obstet Gynecol. 2019 May;220(5):486.e1-486.e11
pubmed: 30707967
Vojnosanit Pregl. 2013 Jan;70(1):46-50
pubmed: 23401929
Prenat Diagn. 2002 Sep;22(9):778-82
pubmed: 12224070
Ultrasound Obstet Gynecol. 2007 Oct;30(5):742-9
pubmed: 17899573
BJOG. 2000 Oct;107(10):1265-70
pubmed: 11028579
Ultrasound Obstet Gynecol. 2005 Mar;25(3):221-6
pubmed: 15736186
BMJ. 2001 Nov 24;323(7323):1213-7
pubmed: 11719411
Obstet Gynecol Sci. 2017 Mar;60(2):154-162
pubmed: 28344956
PLoS One. 2017 Jan 9;12(1):e0169311
pubmed: 28068394
Ultrasound Obstet Gynecol. 2011 Mar;37(3):341-7
pubmed: 20737455
Prenat Diagn. 2012 Aug;32(8):724-9
pubmed: 22553082
Clin Chem Lab Med. 2016 Jan;54(1):117-23
pubmed: 26544105
Am J Obstet Gynecol. 2004 Oct;191(4):1446-51
pubmed: 15507981
BJOG. 2003 Mar;110(3):281-6
pubmed: 12628268
Hum Reprod. 2008 Sep;23(9):1968-75
pubmed: 18544579
Prenat Diagn. 2013 Sep;33(9):839-47
pubmed: 23613261
Am J Obstet Gynecol. 2000 Mar;182(3):607-11
pubmed: 10739516
J Clin Endocrinol Metab. 2002 Apr;87(4):1762-7
pubmed: 11932314