Polyurethane foam for skin graft fixation in clinical-relevant ovine burn wound model for wound repair and regeneration research.
Allogenous skin graft
Autologous skin graft
Burn wound healing
Non-adhesive hydrocellular foam dressing
Polyurethane foam
Sheep
Journal
Regenerative therapy
ISSN: 2352-3204
Titre abrégé: Regen Ther
Pays: Netherlands
ID NLM: 101709085
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
19
01
2020
revised:
15
02
2020
accepted:
04
04
2020
entrez:
4
6
2020
pubmed:
4
6
2020
medline:
4
6
2020
Statut:
epublish
Résumé
The availability of clinical-relevant large animal models for research in wound healing study is limited. Although a few reports described the wound dressing fixation method using polyurethane foam in patients, no animal studies were conducted to investigate efficacy of the polyurethane foam in grafted burn wounds. In the present study, we report a simple fixation method of grafted burned skin using polyurethane foam dressing (Allevyn Non-Adhesive, smith & nephew, UK) in a clinically relevant ovine grafted burn wound model. The dressing was removed at postoperative day 7 after skin graft. The grafted skin was completely engrafted without any complications. This method was safe and easy to perform and associated with good engraftment without any complications. We believe that the polyurethane foam fixation method may be successfully used in clinical practice as well as in preclinical studies for grafted burn wound repair and regeneration research.
Identifiants
pubmed: 32490059
doi: 10.1016/j.reth.2020.04.007
pii: S2352-3204(20)30026-2
pmc: PMC7256436
doi:
Types de publication
Journal Article
Langues
eng
Pagination
341-343Informations de copyright
© 2020 The Japanese Society for Regenerative Medicine. Production and hosting by Elsevier B.V.
Déclaration de conflit d'intérêts
The authors declare no competing interests.
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