Illuminating Genetic Mysteries of the Dead Sea Scrolls.


Journal

Cell
ISSN: 1097-4172
Titre abrégé: Cell
Pays: United States
ID NLM: 0413066

Informations de publication

Date de publication:
11 06 2020
Historique:
received: 11 02 2020
revised: 01 04 2020
accepted: 23 04 2020
pubmed: 4 6 2020
medline: 5 1 2021
entrez: 4 6 2020
Statut: ppublish

Résumé

The discovery of the 2,000-year-old Dead Sea Scrolls had an incomparable impact on the historical understanding of Judaism and Christianity. "Piecing together" scroll fragments is like solving jigsaw puzzles with an unknown number of missing parts. We used the fact that most scrolls are made from animal skins to "fingerprint" pieces based on DNA sequences. Genetic sorting of the scrolls illuminates their textual relationship and historical significance. Disambiguating the contested relationship between Jeremiah fragments supplies evidence that some scrolls were brought to the Qumran caves from elsewhere; significantly, they demonstrate that divergent versions of Jeremiah circulated in parallel throughout Israel (ancient Judea). Similarly, patterns discovered in non-biblical scrolls, particularly the Songs of the Sabbath Sacrifice, suggest that the Qumran scrolls represent the broader cultural milieu of the period. Finally, genetic analysis divorces debated fragments from the Qumran scrolls. Our study demonstrates that interdisciplinary approaches enrich the scholar's toolkit.

Identifiants

pubmed: 32492404
pii: S0092-8674(20)30552-3
doi: 10.1016/j.cell.2020.04.046
pii:
doi:

Types de publication

Historical Article Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

1218-1231.e27

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Interests The authors declare no competing interests.

Auteurs

Sarit Anava (S)

Department of Neurobiology, George Wise Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv 6997801, Israel.

Moran Neuhof (M)

Department of Neurobiology, George Wise Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv 6997801, Israel.

Hila Gingold (H)

Department of Neurobiology, George Wise Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv 6997801, Israel.

Or Sagy (O)

Department of Neurobiology, George Wise Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv 6997801, Israel.

Arielle Munters (A)

Human Evolution, Department of Organismal Biology and SciLife Lab, Uppsala University, 751 05 Uppsala, Sweden.

Emma M Svensson (EM)

Human Evolution, Department of Organismal Biology and SciLife Lab, Uppsala University, 751 05 Uppsala, Sweden.

Ebrahim Afshinnekoo (E)

Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10065, USA; The WorldQuant Initiative for Quantitate Prediction, New York, NY 10065, USA.

David Danko (D)

Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10065, USA; The WorldQuant Initiative for Quantitate Prediction, New York, NY 10065, USA.

Jonathan Foox (J)

Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10065, USA; The WorldQuant Initiative for Quantitate Prediction, New York, NY 10065, USA.

Pnina Shor (P)

Dead Sea Scroll Projects, Israel Antiquities Authority, Jerusalem 91710, Israel.

Beatriz Riestra (B)

Dead Sea Scroll Projects, Israel Antiquities Authority, Jerusalem 91710, Israel.

Dorothée Huchon (D)

Steinhardt Museum of Natural History and Israel National Center for Biodiversity Studies, Tel-Aviv University, Tel-Aviv 6997801, Israel; Department of Zoology, George S. Wise Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv 6997801, Israel.

Christopher E Mason (CE)

Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10065, USA; The WorldQuant Initiative for Quantitate Prediction, New York, NY 10065, USA.

Noam Mizrahi (N)

Department of Biblical Studies, The Lester and Sally Entin Faculty of Humanities, Tel Aviv University, Tel-Aviv 6997801, Israel. Electronic address: noam.m.mizrahi@gmail.com.

Mattias Jakobsson (M)

Human Evolution, Department of Organismal Biology and SciLife Lab, Uppsala University, 751 05 Uppsala, Sweden. Electronic address: mattias.jakobsson@ebc.uu.se.

Oded Rechavi (O)

Department of Neurobiology, George Wise Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv 6997801, Israel. Electronic address: odedrechavi@gmail.com.

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Classifications MeSH