IL-21 and IL-5 coordinately induce surface IgA

Animals B-Lymphocytes / immunology Cells, Cultured Cytidine Deaminase / genetics Gene Expression Regulation Immunoglobulin A / metabolism Immunoglobulin D / metabolism Interleukin-5 / metabolism Interleukins / metabolism Lipopolysaccharides / immunology Mice Mice, Inbred C57BL Mice, Transgenic Peyer's Patches / immunology Positive Regulatory Domain I-Binding Factor 1 / genetics Signal Transduction Transforming Growth Factor beta1 / metabolism Tretinoin / metabolism
IL-21 IL-5 IgA Peyer’s patch

Journal

Immunology letters
ISSN: 1879-0542
Titre abrégé: Immunol Lett
Pays: Netherlands
ID NLM: 7910006

Informations de publication

Date de publication:
08 2020
Historique:
received: 24 01 2020
revised: 07 05 2020
accepted: 26 05 2020
pubmed: 4 6 2020
medline: 6 7 2021
entrez: 4 6 2020
Statut: ppublish

Résumé

Intestinal IgA is induced by microbes and food antigens. Peyer's patches (PPs) are known as one of the inductive sites for intestinal IgA production. However, the precise mechanism of IgA induction is as yet unknown. IgA secretion was induced from IgD

Identifiants

DOI: 10.1016/j.imlet.2020.05.004 PMID: 32492473
pubmed: 32492473
pii: S0165-2478(20)30321-7
doi: 10.1016/j.imlet.2020.05.004
pii:
doi:

Substances chimiques

Immunoglobulin A 0
Immunoglobulin D 0
Interleukin-5 0
Interleukins 0
Lipopolysaccharides 0
Transforming Growth Factor beta1 0
Tretinoin 5688UTC01R
Positive Regulatory Domain I-Binding Factor 1 EC 2.1.1.-
AICDA (activation-induced cytidine deaminase) EC 3.5.4.-
Cytidine Deaminase EC 3.5.4.5
interleukin-21 MKM3CA6LT1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

21-27

Informations de copyright

Copyright © 2020 European Federation of Immunological Societies. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors have no commercial and financial conflicts of interest.

Auteurs

Masaaki Hashiguchi (M)

Department of Immunology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, Japan. Electronic address: mhashi@dokkyomed.ac.jp.

Yuji Kashiwakura (Y)

Department of Immunology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, Japan.

Yumiko Kanno (Y)

Department of Immunology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, Japan.

Hidefumi Kojima (H)

Department of Immunology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, Japan.

Tetsuji Kobata (T)

Department of Immunology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, Japan.

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes B › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Cellules › Cellules cultivées › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Aminohydrolases › Nucleoside deaminases › Cytidine deaminase › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Isotypes des immunoglobulines › Immunoglobuline A › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Isotypes des immunoglobulines › Immunoglobuline D › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interleukines › Interleukine-5 › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interleukines › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Toxines bactériennes › Endotoxines › Lipopolysaccharides › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Système lymphatique › Tissu lymphoïde › Plaques de Peyer › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Protéines de répression › Facteur-1 liant le domaine de régulation positive I › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Protéines de la superfamille du TGF bêta › Facteur de croissance transformant bêta › Facteur de croissance transformant bêta-1 › IL-21 and IL-5 coordinately induce surface IgA
questionsmedicales.fr › Facteurs biologiques › Pigments biologiques › Caroténoïdes › Rétinoïdes › Trétinoïne › IL-21 and IL-5 coordinately induce surface IgA