Nutritional Status and Bone Microarchitecture in a Cohort of Systemic Sclerosis Patients.
Absorptiometry, Photon
Adolescent
Adult
Aged
Aged, 80 and over
Body Mass Index
Bone Density
Female
Gastrointestinal Tract
/ metabolism
Humans
Intestinal Absorption
Malabsorption Syndromes
/ etiology
Male
Malnutrition
/ diagnosis
Middle Aged
Nutritional Status
Pilot Projects
Retrospective Studies
Scleroderma, Systemic
/ complications
Young Adult
bone parameters
malnutrition
systemic sclerosis
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
01 Jun 2020
01 Jun 2020
Historique:
received:
06
03
2020
revised:
15
05
2020
accepted:
27
05
2020
entrez:
5
6
2020
pubmed:
5
6
2020
medline:
23
2
2021
Statut:
epublish
Résumé
Systemic sclerosis (SSc) is a connective tissue disease characterized by initial microvascular damage, immune system activation and progressive fibrosis with insufficiency of internal organs. Gastrointestinal (GI) involvement is characterized by atrophy of the smooth muscle and small bowel hypomotility, mainly resulting from an autonomic nerve dysfunction. These modifications significantly affect gut transit and nutrient absorption, thus leading to malnutrition deficit induced by malabsorption. Nutritional deficit induced by malabsorption might also lead to bone alterations. This study aims to evaluate the relationship between malnutrition and bone status. Thirty-six postmenopausal female patients fulfilling the ACR 2013 criteria for SSc underwent dual-energy X-ray absorptiometry scan (DXA) to detect quantitative lumbar spine bone mineral density (BMD) and trabecular bone score (TBS) analysis to detect bone quality. Data from DXA also allow to assess body composition and provide several quantitative parameters, including free fat mass index (FFMI) that identifies the patient with malnutrition (values <15 kg/m
Identifiants
pubmed: 32492873
pii: nu12061632
doi: 10.3390/nu12061632
pmc: PMC7353037
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
Expert Rev Gastroenterol Hepatol. 2013 May;7(4):331-9
pubmed: 23639091
Calcif Tissue Int. 2016 Jul;99(1):23-9
pubmed: 26898382
Lancet. 2017 Oct 7;390(10103):1685-1699
pubmed: 28413064
Semin Arthritis Rheum. 2005 Feb;34(4):678-82
pubmed: 15692961
PLoS One. 2016 Oct 5;11(10):e0163894
pubmed: 27706206
Aliment Pharmacol Ther. 2006 Mar 15;23(6):691-712
pubmed: 16556171
Bone. 2015 Sep;78:216-24
pubmed: 25988660
Am J Clin Nutr. 2019 Feb 1;109(2):478-486
pubmed: 30624598
J Rheumatol. 2013 Nov;40(11):1881-90
pubmed: 24037552
Curr Gastroenterol Rep. 2001 Oct;3(5):399-407
pubmed: 11560797
Clin Nutr. 2015 Jun;34(3):335-40
pubmed: 25799486
Nutrients. 2019 Nov 09;11(11):
pubmed: 31717475
Clin Exp Rheumatol. 2010 Mar-Apr;28(2 Suppl 58):S42-6
pubmed: 20576213
Clin Rheumatol. 2020 Jan;39(1):227-232
pubmed: 31734774
Clin Exp Rheumatol. 2015 Jul-Aug;33(4 Suppl 91):S190-4
pubmed: 26339898
Adv Clin Exp Med. 2016 Jan-Feb;25(1):185-90
pubmed: 26935513
J Rheumatol. 2017 Dec;44(12):1941-1942
pubmed: 29196550
Nutrition. 2003 Jul-Aug;19(7-8):597-604
pubmed: 12831945
Clin Rheumatol. 2020 Jan;39(1):57-67
pubmed: 31129793
Arch Osteoporos. 2020 Feb 24;15(1):25
pubmed: 32095943
Osteoporos Int. 1994 Nov;4(6):368-81
pubmed: 7696835
Aliment Pharmacol Ther. 2017 Apr;45(7):883-898
pubmed: 28185291
Am J Physiol Gastrointest Liver Physiol. 2008 Jan;294(1):G208-16
pubmed: 17962355
J Bone Miner Res. 2014 Mar;29(3):518-30
pubmed: 24443324
J Clin Densitom. 2009 Apr-Jun;12(2):170-6
pubmed: 19181553
Am J Epidemiol. 1996 Jul 15;144(2):124-34
pubmed: 8678043
Rheumatology (Oxford). 2007 Jan;46(1):150-3
pubmed: 16782730
Arthritis Rheum. 2013 Nov;65(11):2737-47
pubmed: 24122180
Nat Rev Rheumatol. 2010 Oct;6(10):578-87
pubmed: 20703220
PLoS One. 2013 Jun 20;8(6):e66991
pubmed: 23818972
Ann Rheum Dis. 2012 Aug;71(8):1355-60
pubmed: 22615460
Arthritis Res Ther. 2016 Nov 29;18(1):278
pubmed: 27894337
J Gerontol A Biol Sci Med Sci. 2001 Apr;56(4):M212-6
pubmed: 11283193
Int J Mol Sci. 2019 Nov 22;20(23):
pubmed: 31766755
PLoS One. 2017 Jun 9;12(6):e0179062
pubmed: 28598975
Dig Dis Sci. 2018 Apr;63(4):834-844
pubmed: 29464583
Clin Rheumatol. 2010 Dec;29(12):1419-25
pubmed: 20454816
Am J Med. 1993 Jun;94(6):646-50
pubmed: 8506892
Rheumatology (Oxford). 2013 Jun;52(6):1095-100
pubmed: 23382360
Am J Clin Nutr. 2002 Apr;75(4):609-10
pubmed: 11916747
Rheumatology (Oxford). 2018 Sep 1;57(9):1548-1554
pubmed: 29788459
JPEN J Parenter Enteral Nutr. 2016 May;40(4):475-86
pubmed: 25634161
Oral Dis. 2017 Oct;23(7):828-839
pubmed: 27717092
J Clin Gastroenterol. 2008 Jan;42(1):5-12
pubmed: 18097282
RMD Open. 2018 Oct 18;4(Suppl 1):e000782
pubmed: 30402270
Gut. 2006 Dec;55(12):1697-703
pubmed: 16527835
Rheumatology (Oxford). 2010 Sep;49(9):1770-5
pubmed: 20530510
Autoimmun Rev. 2017 May;16(5):548-554
pubmed: 28279841