Liver Cirrhosis Complications Management at the Emergency Department.

Liver cirrhosis ascites emergency hepato-renal syndrome spontaneous bacterial peritonitis variceal hemorrhage

Journal

Reviews on recent clinical trials
ISSN: 1876-1038
Titre abrégé: Rev Recent Clin Trials
Pays: United Arab Emirates
ID NLM: 101270873

Informations de publication

Date de publication:
Historique:
received: 04 02 2020
revised: 16 04 2020
accepted: 27 04 2020
pubmed: 5 6 2020
medline: 29 10 2021
entrez: 5 6 2020
Statut: ppublish

Résumé

Liver cirrhosis (LC) of any origin has always been a source of several emergencies for physicians working at the Emergency Department (ER). LC patients can present with several complications that are sometimes difficult to recognize and treat. Thus, we reviewed the literature evidence for the diagnosis and management of several LC related emergencies. We conducted a search on the main medical databases for papers, reviews, metanalyses, case series, and RCTs using the following keywords and their associations: liver cirrhosis, variceal hemorrhage, ascites, hepatic encephalopathy, spontaneous bacterial peritonitis, hepato-renal syndrome, emergency. Main LC emergencies are upper gastrointestinal hemorrhage, decompensated ascites and spontaneous bacterial peritonitis, hepatic encephalopathy, hepato-renal syndrome. Their management is partly medical and interventional. Very often, the final cure of some complications, such as hepato-renal syndrome, is represented by liver transplantation. Although LC prevalence is going to fall in the following years, due to HBV and HCV optimized treatments, its complications represent a significant admission percentage at the ER and challenge for physicians' skills.

Sections du résumé

BACKGROUND AND AIMS OBJECTIVE
Liver cirrhosis (LC) of any origin has always been a source of several emergencies for physicians working at the Emergency Department (ER). LC patients can present with several complications that are sometimes difficult to recognize and treat. Thus, we reviewed the literature evidence for the diagnosis and management of several LC related emergencies.
METHODS METHODS
We conducted a search on the main medical databases for papers, reviews, metanalyses, case series, and RCTs using the following keywords and their associations: liver cirrhosis, variceal hemorrhage, ascites, hepatic encephalopathy, spontaneous bacterial peritonitis, hepato-renal syndrome, emergency.
RESULTS RESULTS
Main LC emergencies are upper gastrointestinal hemorrhage, decompensated ascites and spontaneous bacterial peritonitis, hepatic encephalopathy, hepato-renal syndrome. Their management is partly medical and interventional. Very often, the final cure of some complications, such as hepato-renal syndrome, is represented by liver transplantation.
CONCLUSION CONCLUSIONS
Although LC prevalence is going to fall in the following years, due to HBV and HCV optimized treatments, its complications represent a significant admission percentage at the ER and challenge for physicians' skills.

Identifiants

pubmed: 32493202
pii: RRCT-EPUB-107076
doi: 10.2174/1574887115666200603160816
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

331-338

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Auteurs

Emidio Scarpellini (E)

Internal Medicine Unit, "Madonna del Soccorso" General Hospital, San Benedetto del Tronto, Italy.

Carmelo Luigiano (C)

Endoscopy Unit, ASST Santi Paolo e Carlo, Milan, Italy.

Gianluca Svegliati-Baroni (G)

Gastroenterology Clinic, "Riuniti University Hospital", Polytechnics University of Marche, Ancona, Italy.

Dan Dumitrascu (D)

Gastroenterology Unit, Cluj University, Cluj-Napoca, Romania.

Tiziana Larussa (T)

Department of Health Sciences, University "Magna Græcia", Catanzaro, Italy.

Valeria Santori (V)

Gastroenterology Clinic, "Riuniti University Hospital", Polytechnics University of Marche, Ancona, Italy.

Francesco Luzza (F)

Department of Health Sciences, University "Magna Græcia", Catanzaro, Italy.

Ludovico Abenavoli (L)

Department of Health Sciences, University "Magna Græcia", Catanzaro, Italy.

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Classifications MeSH