Comparison of perioperative outcomes in elderly (age ≧ 75 years) vs. younger men undergoing robot-assisted radical prostatectomy.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2020
2020
Historique:
received:
13
10
2019
accepted:
19
05
2020
entrez:
5
6
2020
pubmed:
5
6
2020
medline:
28
8
2020
Statut:
epublish
Résumé
To investigate perioperative, oncologic, and functional outcomes of robot-assisted radical prostatectomy (RARP) in men of age ≥ 75 years in comparison with younger men. From November 2011 to December 2018, six hundred and thirty patients with prostate cancer underwent robot-assisted radical prostatectomy (RARP). A total of 614 patients were analyzed after excluding 16 patients who were treated with hormone therapy prior to RARP. Patients were divided into 2 groups based on their age (age ≥ 75 years: N = 46 patients and age < 75 years: N = 568 patients). Perioperative parameters regarding oncologic/functional outcomes and complication status were compared between the 2 groups. Clavien-Dindo classification was used to classify perioperative complications. Clinical and pathological status including stage, positive margin, continence, and potency status after RARP were analyzed. Five-hundred sixty-eight and forty-six men were of age <75 and ≥ 75 years, respectively. There were no significant differences between the 2 groups in terms of oncologic outcomes (positive resection margin rate and PSA failure). The duration of hospitalization was longer in older patients but was not statistically significant (P = 0.051). A total number of Clavien ≥3 complications that occurred within a month after RARP were 15 (2.6%) and 2 (4.3%) in younger men (age < 75 years) and older men (age ≥ 75 years), respectively (P = 0.359). The present study showed that the oncologic and surgical outcomes in the elderly group were similar to those in the younger population. However, the duration of hospitalization seemed to be longer in older patients (age ≥ 75 years), despite similar complication rates.
Identifiants
pubmed: 32497131
doi: 10.1371/journal.pone.0234113
pii: PONE-D-19-28595
pmc: PMC7272059
doi:
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0234113Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Yonsei Med J. 2016 Sep;57(5):1165-77
pubmed: 27401648
J Clin Oncol. 2003 Sep 1;21(17):3318-27
pubmed: 12947068
Eur Urol. 2011 May;59(5):684-98
pubmed: 21324583
Aging Male. 2017 Jun;20(2):102-109
pubmed: 28084133
West J Med. 1996 Jul-Aug;165(1-2):26-30
pubmed: 8855681
World J Urol. 2009 Oct;27(5):637-42
pubmed: 19396604
Anticancer Res. 2018 Nov;38(11):6529-6535
pubmed: 30396982
Eur Urol. 2016 Nov;70(5):862-874
pubmed: 27289567
Eur Urol. 2012 Apr;61(4):679-85
pubmed: 22206800
Ann Surg. 2004 Aug;240(2):205-13
pubmed: 15273542
Eur Urol. 2010 Mar;57(3):363-70
pubmed: 19944519
Int J Urol. 2016 Feb;23(2):160-6
pubmed: 26502293
Curr Oncol. 2013 Dec;20(6):e522-31
pubmed: 24311952
Int J Urol. 2017 Oct;24(10):749-756
pubmed: 28697538
Medicine (Baltimore). 2019 May;98(22):e15770
pubmed: 31145297
BJU Int. 2010 Sep;106(6):791-5
pubmed: 20201836
Surgery. 1992 May;111(5):518-26
pubmed: 1598671
N Engl J Med. 2002 Sep 12;347(11):781-9
pubmed: 12226148
Anticancer Res. 2012 May;32(5):2085-9
pubmed: 22593493
J Endourol. 2010 Sep;24(9):1457-61
pubmed: 20673148
Yonsei Med J. 2014 Mar;55(2):316-23
pubmed: 24532498
Eur Urol. 2016 Jul;70(1):21-30
pubmed: 26700655
BJU Int. 2009 Jul;104(2):274-81
pubmed: 19594519
Urol Oncol. 2007 Jul-Aug;25(4):291-7
pubmed: 17628294
Indian J Urol. 2015 Jul-Sep;31(3):229-33
pubmed: 26166967
Int J Radiat Oncol Biol Phys. 2001 Nov 1;51(3):614-23
pubmed: 11597800
J Robot Surg. 2015 Sep;9(3):201-9
pubmed: 26531200
BJU Int. 2009 Nov;104(10):1492-5
pubmed: 19583731