Outbreak of hepatitis C virus infections originating from a breach in safe injection practices before contrast-enhanced computed tomography scanning.


Journal

The Journal of hospital infection
ISSN: 1532-2939
Titre abrégé: J Hosp Infect
Pays: England
ID NLM: 8007166

Informations de publication

Date de publication:
Nov 2020
Historique:
received: 08 01 2020
accepted: 26 05 2020
pubmed: 5 6 2020
medline: 2 7 2021
entrez: 5 6 2020
Statut: ppublish

Résumé

Four patients who underwent contrast-enhanced computed tomography (CT) scanning were infected with hepatitis C virus from a contaminated multi-dose vial of NaCl. The outbreak likely occurred due to a breach in safe injection practices, resulting in contamination of the vial. Not all patients exposed to the same vial were infected. The uneven distribution of infections could be attributed to a stochastic effect of a low infectious dose. This implies that outbreak investigations need to be extended to all patients scheduled before and after the first identified infected patient to confirm or rule out nosocomial transmission.

Identifiants

pubmed: 32497652
pii: S0195-6701(20)30281-4
doi: 10.1016/j.jhin.2020.05.041
pii:
doi:

Substances chimiques

Contrast Media 0
Hepatitis Antibodies 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

600-604

Informations de copyright

Copyright © 2020 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Auteurs

C Balmelli (C)

Division of Infection Control and Hospital Epidemiology, Ente Ospedaliero Cantonale, Bellinzona, Ticino, Switzerland. Electronic address: carlo.balmelli@eoc.ch.

G Merlani (G)

Division of Public Health, Canton Ticino, Bellinzona, Ticino, Switzerland.

G Martinetti (G)

Division of Infection Control and Hospital Epidemiology, Ente Ospedaliero Cantonale, Bellinzona, Ticino, Switzerland.

D Reinholz (D)

Division of Public Health, Canton Ticino, Bellinzona, Ticino, Switzerland. Electronic address: danuta.zemp@sg.ch.

S Paolucci (S)

Fondazione IRCCS Policlinico San Matteo, Pavia, Lombardy, Italy.

F Baldanti (F)

University of Pavia, Pavia, Lombardy, Italy.

A Piralla (A)

Fondazione IRCCS Policlinico San Matteo, Pavia, Lombardy, Italy; University of Pavia, Pavia, Lombardy, Italy.

F Del Grande (F)

Clinica di Radiologia EOC, Istituto di Imaging della Svizzera Italiana, Ospedale Regionale di Lugano, Ticino, Switzerland.

E Bernasconi (E)

Division of Infectious Diseases, Ospedale Regionale di Lugano, Lugano, Ticino, Switzerland.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH