Impact of ultra-low dose CT acquisition on semi-automated RECIST tool in the evaluation of malignant focal liver lesions.

Artificial intelligence Computed X-ray tomography Liver Low dose CT protocol Response evaluation criteria in solid tumours (RECIST)

Journal

Diagnostic and interventional imaging
ISSN: 2211-5684
Titre abrégé: Diagn Interv Imaging
Pays: France
ID NLM: 101568499

Informations de publication

Date de publication:
Historique:
received: 06 04 2020
revised: 05 05 2020
accepted: 06 05 2020
pubmed: 6 6 2020
medline: 10 7 2021
entrez: 6 6 2020
Statut: ppublish

Résumé

To compare the evaluation of malignant focal liver lesions (FLLs) using a semi-automated RECIST tool with a standard and an ultra-low dose (ULD) computed tomography (CT) protocol. Thirty-four patients with malignant FLLs underwent two abdominal-pelvic CT examinations one using a standard protocol and one using an ULD protocol. There were 23 men and 11 women with a mean age 64.3±14.4 (SD) years (range: 22-91 years). Dosimetric indicators were recorded, and effective dose was calculated for both examinations. Mean malignant FLL attenuation, image noise and contrast-to-noise-ratio (CNR) were compared. The largest malignant FLL per patient was evaluated using the semi-automated RECIST tool to determine longest axis length, longest orthogonal axis length, volume and World Health Organisation area. Dosimetric values were significantly reduced by -56% with ULD compared to standard protocol. No differences in mean malignant FLL attenuation values were found between the two protocols. Image noise was significantly increased for all locations (P<0.05) with ULD compared to standard protocol, and CNR was significantly reduced (P<0.05). On the 34 malignant FLLs analyzed, six semi-automated shapes non-concordant with radiologist's visual impression were highlighted with the software, including one FLL (1/34; 3%) with standard CT acquisition only, three FLLs (3/34; 9%) with ULD CT acquisition only and two FLLs (2/34; 6%) with both CT acquisitions. After manual editing, the concordance of the values of the studied criteria between both acquisitions was good and no significant difference was reported. Semi-automated RECIST tool demonstrates good performances using ULD CT protocol. It could be used in routine clinical practice with a ULD protocol for follow-up studies in patients with known malignant FLL.

Identifiants

pubmed: 32499192
pii: S2211-5684(20)30127-3
doi: 10.1016/j.diii.2020.05.003
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

473-479

Informations de copyright

Copyright © 2020 Société française de radiologie. Published by Elsevier Masson SAS. All rights reserved.

Auteurs

A Hamard (A)

Department of Medical Imaging, CHU of Nîmes, University of Montpellier, Medical Imaging Group Nîmes, EA 2415, 30029 Nîmes cedex 9, France. Electronic address: aymeric.hamard@chu-nimes.fr.

J Frandon (J)

Department of Medical Imaging, CHU of Nîmes, University of Montpellier, Medical Imaging Group Nîmes, EA 2415, 30029 Nîmes cedex 9, France.

A Larbi (A)

Department of Medical Imaging, CHU of Nîmes, University of Montpellier, Medical Imaging Group Nîmes, EA 2415, 30029 Nîmes cedex 9, France.

J Goupil (J)

Department of Medical Imaging, CHU of Nîmes, University of Montpellier, Medical Imaging Group Nîmes, EA 2415, 30029 Nîmes cedex 9, France.

H De Forges (H)

Department of Medical Imaging, CHU of Nîmes, University of Montpellier, Medical Imaging Group Nîmes, EA 2415, 30029 Nîmes cedex 9, France.

J-P Beregi (JP)

Department of Medical Imaging, CHU of Nîmes, University of Montpellier, Medical Imaging Group Nîmes, EA 2415, 30029 Nîmes cedex 9, France.

J Greffier (J)

Department of Medical Imaging, CHU of Nîmes, University of Montpellier, Medical Imaging Group Nîmes, EA 2415, 30029 Nîmes cedex 9, France.

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