A lower X-gate in TASK channels traps inhibitors within the vestibule.
Anesthetics
/ pharmacology
Animals
Crystallography, X-Ray
Electric Conductivity
Female
Humans
Ion Channel Gating
/ drug effects
Models, Molecular
Mutation
Nerve Tissue Proteins
/ antagonists & inhibitors
Oocytes
/ drug effects
Patch-Clamp Techniques
Potassium Channels, Tandem Pore Domain
/ antagonists & inhibitors
Xenopus laevis
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
08
07
2019
accepted:
12
03
2020
pubmed:
6
6
2020
medline:
22
9
2020
entrez:
6
6
2020
Statut:
ppublish
Résumé
TWIK-related acid-sensitive potassium (TASK) channels-members of the two pore domain potassium (K
Identifiants
pubmed: 32499642
doi: 10.1038/s41586-020-2250-8
pii: 10.1038/s41586-020-2250-8
doi:
Substances chimiques
Anesthetics
0
Nerve Tissue Proteins
0
Potassium Channels, Tandem Pore Domain
0
potassium channel subfamily K member 3
1HQ3YCN4GS
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
443-447Subventions
Organisme : Wellcome Trust
ID : 106169/Z/14/Z
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 109114/Z/15/Z
Pays : United Kingdom
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