Dynamic Supraspliceosomes Are Assembled on Different Transcripts Regardless of Their Intron Number and Splicing State.
MS2-tagged supraspliceosomes
pre-mRNA splicing
specific supraspliceosomes
splicing factors
splicing inhibition
Journal
Frontiers in genetics
ISSN: 1664-8021
Titre abrégé: Front Genet
Pays: Switzerland
ID NLM: 101560621
Informations de publication
Date de publication:
2020
2020
Historique:
received:
16
09
2019
accepted:
31
03
2020
entrez:
6
6
2020
pubmed:
6
6
2020
medline:
6
6
2020
Statut:
epublish
Résumé
Splicing and alternative splicing of pre-mRNA are key sources in the formation of diversity in the human proteome. These processes have a central role in the regulation of the gene expression pathway. Yet, how spliceosomes are assembled on a multi-intronic pre-mRNA is at present not well understood. To study the spliceosomes assembled
Identifiants
pubmed: 32499811
doi: 10.3389/fgene.2020.00409
pmc: PMC7243799
doi:
Types de publication
Journal Article
Langues
eng
Pagination
409Subventions
Organisme : NIGMS NIH HHS
ID : R01 GM079549
Pays : United States
Informations de copyright
Copyright © 2020 Sebbag-Sznajder, Brody, Hochberg-Laufer, Shav-Tal, Sperling and Sperling.
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