Bilirubin-A Possible Prognostic Mortality Marker for Patients with ECLS.
ECLS
bilirubin
liver function
mortality
prognosis
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
03 Jun 2020
03 Jun 2020
Historique:
received:
15
04
2020
revised:
13
05
2020
accepted:
02
06
2020
entrez:
7
6
2020
pubmed:
7
6
2020
medline:
7
6
2020
Statut:
epublish
Résumé
Extracorporeal life support (ECLS) is a promising therapeutic option for patients with refractory cardiogenic shock. However, as the mortality rate still remains high, there is a need for early outcome parameters reflecting therapy success or futility. Therefore, we investigated whether liver enzyme levels could serve as prognostic mortality markers for patients with ECLS. The present study is a retrospective single-center cohort study. Adult patients >18 years of age who received ECLS therapy between 2011 and 2018 were included. Bilirubin, glutamic-oxaloacetic transaminase (GOT), and glutamic-pyruvic-transaminase (GPT) serum levels were analyzed at day 5 after the start of the ECLS therapy. The primary endpoint of this study was all-cause in-hospital mortality. A total of 438 patients received ECLS during the observation period. Based on the inclusion criteria, 298 patients were selected for the statistical analysis. The overall mortality rate was 42.6% (
Identifiants
pubmed: 32503278
pii: jcm9061727
doi: 10.3390/jcm9061727
pmc: PMC7356548
pii:
doi:
Types de publication
Journal Article
Langues
eng
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