Reconstructing Mayaro virus circulation in French Guiana shows frequent spillovers.
Adolescent
Adult
Alphavirus Infections
/ blood
Antibodies, Viral
/ blood
Arboviruses
/ immunology
Chikungunya virus
/ immunology
Child
Child, Preschool
Communicable Diseases, Emerging
/ blood
Cross Reactions
/ immunology
Cross-Sectional Studies
Epidemiological Monitoring
Female
French Guiana
/ epidemiology
Humans
Immunoglobulin G
/ blood
Infant
Male
Middle Aged
Rural Health
/ statistics & numerical data
Seroepidemiologic Studies
Young Adult
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
05 06 2020
05 06 2020
Historique:
received:
19
09
2019
accepted:
03
05
2020
entrez:
7
6
2020
pubmed:
7
6
2020
medline:
22
8
2020
Statut:
epublish
Résumé
Characterizing the circulation of Mayaro virus (MAYV), an emerging arbovirus threat, is essential for risk assessment but challenging due to cross-reactivity with other alphaviruses such as chikungunya virus (CHIKV). Here, we develop an analytical framework to jointly assess MAYV epidemiology and the extent of cross-reactivity with CHIKV from serological data collected throughout French Guiana (N = 2697). We find strong evidence of an important sylvatic cycle for MAYV with most infections occurring near the natural reservoir in rural areas and in individuals more likely to go to the forest (i.e., adult males) and with seroprevalences of up to 18% in some areas. These findings highlight the need to strengthen MAYV surveillance in the region and showcase how modeling can improve interpretation of cross-reacting assays.
Identifiants
pubmed: 32503971
doi: 10.1038/s41467-020-16516-x
pii: 10.1038/s41467-020-16516-x
pmc: PMC7275077
doi:
Substances chimiques
Antibodies, Viral
0
Immunoglobulin G
0
Types de publication
Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2842Commentaires et corrections
Type : ErratumIn
Références
Esposito, D. L. A. & Fonseca, B. Will Mayaro virus be responsible for the next outbreak of an arthropod-borne virus in Brazil? Braz. J. Infect. Dis. 21, 540–544 (2017).
doi: 10.1016/j.bjid.2017.06.002
pubmed: 28688628
pmcid: 9425496
Hotez, P. J. & Murray, K. O. Dengue, West Nile virus, chikungunya, Zika-and now Mayaro. PLoS Negl. Trop. Dis. 11, e0005462 (2017).
doi: 10.1371/journal.pntd.0005462
pubmed: 28859086
pmcid: 5578481
Mavian, C. et al. Emergence of recombinant Mayaro virus strains from the Amazon basin. Sci. Rep 7, 8718 (2017).
doi: 10.1038/s41598-017-07152-5
pubmed: 28821712
pmcid: 5562835
Lednicky, J. et al. Mayaro virus in child with acute Febrile Illness, Haiti, 2015. Emerg. Infect. Dis. 22, 2000–2002 (2016).
doi: 10.3201/eid2211.161015
pubmed: 27767924
pmcid: 5088037
Paniz-Mondolfi, A. E., Rodriguez-Morales, A. J., Blohm, G., Marquez, M. & Villamil-Gomez, W. E. ChikDenMaZika syndrome: the challenge of diagnosing arboviral infections in the midst of concurrent epidemics. Ann. Clin. Microbiol. Antimicrob. 15, 42 (2016).
doi: 10.1186/s12941-016-0157-x
pubmed: 27449770
pmcid: 4957883
Wolfe, N. D., Daszak, P., Kilpatrick, A. M. & Burke, D. S. Bushmeat hunting, deforestation, and prediction of zoonoses emergence. Emerg. Infect. Dis. 11, 1822–1827 (2005).
doi: 10.3201/eid1112.040789
pubmed: 16485465
pmcid: 3367616
Halsey, E. S. et al. Mayaro virus infection, Amazon Basin region, Peru, 2010-2013. Emerg. Infect. Dis. 19, 1839–1842 (2013).
doi: 10.3201/eid1911.130777
pubmed: 24210165
pmcid: 3837653
Acosta-Ampudia, Y. et al. Mayaro: an emerging viral threat? Emerg. Microbes Infect. 7, 163 (2018).
doi: 10.1038/s41426-018-0163-5
pubmed: 30254258
pmcid: 6156602
Brunini, S. et al. High frequency of Mayaro virus IgM among febrile patients, Central Brazil. Emerg. Infect. Dis. 23, 1025–1026 (2017).
doi: 10.3201/eid2306.160929
pubmed: 28518022
pmcid: 5443426
PAHO/WHO. 1 May 2019: Mayaro fever-epidemiological alert. https://www.paho.org/hq/index.php?option=com_content&view=article&id=15123:1-may-2019-mayaro-fever-epidemiological-alert&Itemid=42346&lang=en (2019).
Salje, H. et al. Nationally-representative serostudy of dengue in Bangladesh allows generalizable disease burden estimates. Elife 8, e42869 (2019).
doi: 10.7554/eLife.42869
pubmed: 30958263
pmcid: 6513551
Pezzi, L. et al. GloPID-R report on Chikungunya, O’nyong-nyong and Mayaro virus, part I: biological diagnostics. Antiviral Res. 166, 66–81 (2019).
doi: 10.1016/j.antiviral.2019.03.009
pubmed: 30905821
Cellule de l’institut de veille sanitaire en région Antilles-Guyane. Point Epidémiologique de janvier 2015: Le chikungunya dans les Antilles 1–6, (in French, 2015).
Cellule de l’institut de veille sanitaire en région Antilles-Guyane. Point Epidémiologique de juillet 2014: Le chikungunya dans les Antilles 1–7, (in French, 2014).
Fritzell, C. et al. Knowledge, attitude and practices of vector-borne disease prevention during the emergence of a new arbovirus: implications for the control of Chikungunya virus in French Guiana. PLoS Negl. Trop. Dis. 10, e0005081 (2016).
doi: 10.1371/journal.pntd.0005081
pubmed: 27802275
pmcid: 5089683
Llagonne-Barets, M. et al. A case of Mayaro virus infection imported from French Guiana. J. Clin. Virol. 77, 66–68 (2016).
doi: 10.1016/j.jcv.2016.02.013
pubmed: 26921736
Talarmin, A. et al. Mayaro virus fever in French Guiana: isolation, identification, and seroprevalence. Am. J. Trop. Med. Hyg. 59, 452–456 (1998).
doi: 10.4269/ajtmh.1998.59.452
pubmed: 9749643
Flamand, C. et al. Impact of Zika virus emergence in French Guiana: a large general-population seroprevalence survey. J. Infect. Dis. 220, 1915–1925 (2019).
doi: 10.1093/infdis/jiz396
pubmed: 31418012
pmcid: 6834069
Aubry, M. et al. Seroprevalence of dengue and Chikungunya virus antibodies, French Polynesia, 2014-2015. Emerg. Infect. Dis. 24, 558–561 (2018).
doi: 10.3201/eid2403.171149
pubmed: 29460745
pmcid: 5823337
Van Bortel, W. et al. Chikungunya outbreak in the Caribbean region, December 2013 to March 2014, and the significance for Europe. Eurosurveillance 19, 20759 (2014).
pubmed: 24721539
Salje, H. et al. How social structures, space, and behaviors shape the spread of infectious diseases using chikungunya as a case study. Proc. Natl Acad. Sci USA 113, 13420–13425 (2016).
doi: 10.1073/pnas.1611391113
pubmed: 27821727
pmcid: 5127331
Epelboin, Y. et al. Successes and failures of sixty years of vector control in French Guiana: what is the next step? Mem. Inst. Oswaldo Cruz 113, e170398 (2018).
doi: 10.1590/0074-02760170398
pubmed: 29538490
pmcid: 5851058
Fritzell, C. et al. Current challenges and implications for dengue, chikungunya and Zika seroprevalence studies worldwide: a scoping review. PLoS Negl. Trop. Dis. 12, e0006533 (2018).
doi: 10.1371/journal.pntd.0006533
pubmed: 30011271
pmcid: 6062120
Cao-Lormeau, V. M. et al. Guillain-Barre Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study. Lancet 387, 1531–1539 (2016).
doi: 10.1016/S0140-6736(16)00562-6
pubmed: 26948433
pmcid: 5444521
Cauchemez, S. et al. Household transmission of 2009 pandemic influenza A (H1N1) virus in the United States. N. Engl. J. Med. 361, 2619–2627 (2009).
doi: 10.1056/NEJMoa0905498
pubmed: 20042753
Stan Development Team. RStan: the R interface to Stan. R package version 2.19.3. http://mc-stan.org (2020).