Serratane triterpenoids from Lycopodium complanatum and their anti-cancer and anti-inflammatory activities.

Animals Anti-Inflammatory Agents / pharmacology Antineoplastic Agents, Phytogenic / pharmacology Cell Line, Tumor Humans Lycopodium / chemistry Mice Nitric Oxide / metabolism RAW 264.7 Cells Triterpenes / pharmacology
Anti-cancer activities Anti-inflammatory effects Lycopodium complanatum Serratane triterpenoids

Journal

Bioorganic chemistry
ISSN: 1090-2120
Titre abrégé: Bioorg Chem
Pays: United States
ID NLM: 1303703

Informations de publication

Date de publication:
08 2020
Historique:
received: 05 02 2020
revised: 04 04 2020
accepted: 20 05 2020
pubmed: 7 6 2020
medline: 12 3 2021
entrez: 7 6 2020
Statut: ppublish

Résumé

Phytochemical investigation of the ethyl acetate fraction of Lycopodium complanatum led to eight new serratane triterpenoids (lycomplanatums A-H, 1-8), along with five known analogues (9-13). Their structures were elucidated by extensive spectroscopic methods, including 1D/2D NMR, HRESIMS, and DFT GIAO

Identifiants

DOI: 10.1016/j.bioorg.2020.103959 PMID: 32505046
pubmed: 32505046
pii: S0045-2068(20)30276-5
doi: 10.1016/j.bioorg.2020.103959
pii:
doi:

Substances chimiques

Anti-Inflammatory Agents 0
Antineoplastic Agents, Phytogenic 0
Triterpenes 0
Nitric Oxide 31C4KY9ESH

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

103959

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest There is no conflict of interest to declare.

Auteurs

Wenhao Zhou (W)

Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.

Fenghua Kang (F)

Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.

Lili Huang (L)

Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.

Jing Li (J)

Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.

Wenxuan Wang (W)

Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.

Ling Xiao (L)

Xiangya School of Basic Medical Sciences, Central South University, Changsha 410013, PR China.

Qiwan Wen (Q)

Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.

Xia Yu (X)

Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.

Yangrui Xu (Y)

Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.

Zhenxing Zou (Z)

Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.

Hui Zhou (H)

Department of Lymphoma Hematology, Hunan Cancer Hospital, ChangSha 410006, PR China.

Hui Zang (H)

Xiangya School of Basic Medical Sciences, Central South University, Changsha 410013, PR China.

Siwei Chen (S)

Xiangya School of Basic Medical Sciences, Central South University, Changsha 410013, PR China.

Kangping Xu (K)

Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China. Electronic address: xukp395@csu.edu.cn.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Serratane triterpenoids from Lycopodium...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-inflammatoires › Serratane triterpenoids from Lycopodium...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Antinéoplasiques d'origine végétale › Serratane triterpenoids from Lycopodium...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Serratane triterpenoids from Lycopodium...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Serratane triterpenoids from Lycopodium...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Lycopodiaceae › Lycopodium › Serratane triterpenoids from Lycopodium...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Serratane triterpenoids from Lycopodium...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Oxydes d'azote › Monoxyde d'azote › Serratane triterpenoids from Lycopodium...
questionsmedicales.fr › Cellules › Cellules RAW 264.7 › Serratane triterpenoids from Lycopodium...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Triterpènes › Serratane triterpenoids from Lycopodium...