COVID-19: Loss of bridging between innate and adaptive immunity?
Adaptive immunity
COVID-19
Cytokines
Innate immunity
Interferons (IFNs)
SARS-CoV2
Journal
Medical hypotheses
ISSN: 1532-2777
Titre abrégé: Med Hypotheses
Pays: United States
ID NLM: 7505668
Informations de publication
Date de publication:
Nov 2020
Nov 2020
Historique:
received:
17
04
2020
revised:
08
05
2020
accepted:
21
05
2020
pubmed:
7
6
2020
medline:
23
12
2020
entrez:
7
6
2020
Statut:
ppublish
Résumé
COVID-19 has spread to most countries in the world. However, there are some striking differences in how COVID-19 is behaving in different age groups. While data on COVID-19 is limited, children appear to be less susceptible to severe disease. These unique characteristics may be considered as a potential link to understanding the immune system and response in COVID-19 and lead to an effective cure to the disease. We suggest a possible role of loss of bridging between innate and adaptive immunity in COVID-19 and a potential treatment modality also discussed.
Identifiants
pubmed: 32505066
pii: S0306-9877(20)30863-X
doi: 10.1016/j.mehy.2020.109861
pmc: PMC7245229
pii:
doi:
Substances chimiques
Cytokines
0
Interferons
9008-11-1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
109861Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.
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