Risk-stratifying clinicopathologic criteria for ovarian preservation in premenopausal women with early stage low-risk endometrial cancer.
Clinicopathologic criteria
Endometrial cancer
Ovarian preservation
Preoperative criteria
Recurrence
Survival
Journal
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
ISSN: 1879-3479
Titre abrégé: Int J Gynaecol Obstet
Pays: United States
ID NLM: 0210174
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
22
10
2019
revised:
05
04
2020
accepted:
31
05
2020
pubmed:
9
6
2020
medline:
9
3
2021
entrez:
8
6
2020
Statut:
ppublish
Résumé
To establish the rate of occult ovarian micro-metastases in early stage disease and to provide an eligibility framework for providers to consider ovarian preservation in a patient population with presumed early stage disease. A retrospective review from January 2005 to December 2010 identified women with presumed early stage endometrial cancer from a single institutional database. Inclusion criteria included: (1) FIGO grade 1 endometrioid endometrial cancer on endometrial biopsy; or (2) the same pathology as (1) on frozen section specimen with less than 50% myometrial biopsy; and (3) no evidence of metastatic disease on preoperative imaging or visible metastatic disease in the peritoneal cavity. Of the 52 patients, 86.5% were diagnosed with stage IA and 11.5% were diagnosed with stage II disease. One patient (1.9%) had microscopic adnexal involvement in a fallopian tube, which upstaged her to stage IIA disease. None of the patients had ovarian involvement. Preservation of the ovaries appears to be a safe and viable option for premenopausal women who are diagnosed with presumed early stage endometrioid endometrial cancer. It is believed that ovarian preservation in this select population will provide them with significant health benefits and improve their quality of life.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
385-391Informations de copyright
© 2020 International Federation of Gynecology and Obstetrics.
Références
Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016. CA Cancer J Clin. 2016;66:7-30.
Wright JD, Buck AM, Shah M, et al. Safety of ovarian preservation in premenopausal women with endometrial cancer. J Clin Oncol. 2009;27:1214-1219.
National Cancer Institute. Surveillance E, and End Results Program, Cancer Stat Facts: Uterine Cancer.
Erekson EA, Martin DK, Ratner ES. Oophorectomy: The debate between ovarian conservation and elective oophorectomy. Menopause. 2013;20:110-114.
Atsma F, Bartelink ML, Grobbee DE, et al. Postmenopausal status and early menopause as independent risk factors for cardiovascular disease: A meta-analysis. Menopause. 2006;13:265-279.
Parker WH, Broder MS, Liu Z, et al. Ovarian conservation at the time of hysterectomy for benign disease. Clin Obstet Gynecol. 2007;50:354-361.
Rivera CM, Grossardt BR, Rhodes DJ, et al. Increased cardiovascular mortality after early bilateral oophorectomy. Menopause. 2009;16:15-23.
Jia P, Zhang Y. Ovarian preservation improves overall survival in young patients with early-stage endometrial cancer. Oncotarget. 2017;8:59940-59949.
Gu H, Li J, Gu Y, et al. Survival impact of ovarian preservation on women with early-stage endometrial cancer: A systematic review and meta-analysis. Int J Gynecol Cancer. 2017;27:77-84.
Hou T, Sun Y, Li J, et al. The safety of ovarian preservation in stage I endometrial endometrioid adenocarcinoma based on propensity score matching. Comb Chem High Throughput Screen. 2017;20:647-655.
Lau HY, Chen MY, Ke YM, et al. Outcome of ovarian preservation during surgical treatment for endometrial cancer: A Taiwanese Gynecologic Oncology Group study. Taiwan J Obstet Gynecol. 2015;54:532-536.
Matsuo K, Cripe JC, Kurnit KC, et al. Recurrence, death, and secondary malignancy after ovarian conservation for young women with early-stage low-grade endometrial cancer. Gynecol Oncol. 2019;155:39-50.
Wang J, Li XM. Meta-analysis of prognosis of ovarian preserving in young patients with early endometrial cancer. Zhonghua Fu Chan Ke Za Zhi. 2016;51:602-607.
Matsuo K, Machida H, Shoupe D, et al. Ovarian conservation and overall survival in young women with early-stage low-grade endometrial cancer. Obstet Gynecol. 2016;128:761-770.
Matsuo K, Machida H, Stone RL, et al. Risk of subsequent ovarian cancer after ovarian conservation in young women with stage I endometrioid endometrial cancer. Obstet Gynecol. 2017;130:403-410.
Ignatov T, Eggemann H, Burger E, et al. Ovarian metastasis in patients with endometrial cancer: risk factors and impact on survival. J Cancer Res Clin Oncol. 2018;144:1103-1107.
Lin KY, Miller DS, Bailey AA, et al. Ovarian involvement in endometrioid adenocarcinoma of uterus. Gynecol Oncol. 2015;138:532-535.
Barakat RR, Bundy BN, Spirtos NM, et al. Randomized double-blind trial of estrogen replacement therapy versus placebo in stage I or II endometrial cancer: A Gynecologic Oncology Group Study. J Clin Oncol. 2006;24:587-592.
Carneiro MM, Lamaita RM, Ferreira MC, et al. Fertility-preservation in endometrial cancer: Is it safe? Review of the literature. JBRA Assist Reprod. 2016;20:232-239.
Feichtinger M, Rodriguez-Wallberg KA. Fertility preservation in women with cervical, endometrial or ovarian cancers. Gynecol Oncol Res Pract. 2016;3:8.
McKenzie ND, Kennard JA, Ahmad S. Fertility preserving options for gynecologic malignancies: A review of current understanding and future directions. Crit Rev Oncol Hematol. 2018;132:116-124.
Matsuo K, Gualtieri MR, Cahoon SS, et al. Surgical menopause and increased risk of nonalcoholic fatty liver disease in endometrial cancer. Menopause. 2016;23:189-196.
Ward KK, Shah NR, Saenz CC, et al. Cardiovascular disease is the leading cause of death among endometrial cancer patients. Gynecol Oncol. 2012;126:176-179.
Lee TS, Kim JW, Kim TJ, et al. Ovarian preservation during the surgical treatment of early stage endometrial cancer: A nation-wide study conducted by the Korean Gynecologic Oncology Group. Gynecol Oncol. 2009;115:26-31.
Lee TS, Lee JY, Kim JW, et al. Outcomes of ovarian preservation in a cohort of premenopausal women with early-stage endometrial cancer: A Korean Gynecologic Oncology Group study. Gynecol Oncol. 2013;131:289-293.
Wright JD, Jorge S, Tergas AI, et al. Utilization and outcomes of ovarian conservation in premenopausal women with endometrial cancer. Obstet Gynecol. 2016;127:101-108.
Nevadunsky NS, Van Arsdale A, Strickler HD, et al. Obesity and age at diagnosis of endometrial cancer. Obstet Gynecol. 2014;124:300-306.