Inhibitors and fluorescent probes for protein kinase PKAcβ and its S54L mutant, identified in a patient with cortisol producing adenoma.

Adenoma / genetics Cyclic AMP-Dependent Protein Kinase Catalytic Subunits / antagonists & inhibitors Enzyme Inhibitors / pharmacology Fluorescent Dyes / chemistry Humans Hydrocortisone / biosynthesis Mutation
ARC-probes Catalytic subunit β of protein kinase A (PKAcβ) Cushing’s syndrome wild-type-sparing ARC-precursors

Journal

Bioscience, biotechnology, and biochemistry
ISSN: 1347-6947
Titre abrégé: Biosci Biotechnol Biochem
Pays: England
ID NLM: 9205717

Informations de publication

Date de publication:
Sep 2020
Historique:
pubmed: 9 6 2020
medline: 20 4 2021
entrez: 9 6 2020
Statut: ppublish

Résumé

Recently, a mutation was discovered in the gene

Identifiants

DOI: 10.1080/09168451.2020.1772038 PMID: 32507034
pubmed: 32507034
doi: 10.1080/09168451.2020.1772038
doi:

Substances chimiques

Enzyme Inhibitors 0
Fluorescent Dyes 0
Cyclic AMP-Dependent Protein Kinase Catalytic Subunits EC 2.7.11.11
protein kinase A Calpha EC 2.7.11.11
Hydrocortisone WI4X0X7BPJ

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1839-1845

Auteurs

Olivier Etebe Nonga (OE)

Institute of Chemistry, University of Tartu , Tartu, Estonia.
ORCID: 0000-0001-8995-6313

Erki Enkvist (E)

Institute of Chemistry, University of Tartu , Tartu, Estonia.
ORCID: 0000-0001-7375-3765

Friedrich W Herberg (FW)

Department of Biochemistry, University of Kassel , Kassel, Germany.
ORCID: 0000-0001-7117-7653

Asko Uri (A)

Institute of Chemistry, University of Tartu , Tartu, Estonia.
ORCID: 0000-0001-5436-2427

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Classifications MeSH

questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs épithéliales épidermoïdes et glandulaires › Adénomes › Inhibitors and fluorescent probes for protein...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein-Serine-Threonine Kinases › Cyclic Nucleotide-Regulated Protein Kinases › Cyclic AMP-Dependent Protein Kinases › Cyclic AMP-Dependent Protein Kinase Type II › Cyclic AMP-Dependent Protein Kinase Catalytic Subunits › Inhibitors and fluorescent probes for protein...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Inhibitors and fluorescent probes for protein...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Luminescents › Colorants fluorescents › Inhibitors and fluorescent probes for protein...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Inhibitors and fluorescent probes for protein...
questionsmedicales.fr › Hormones corticosurrénaliennes › Hydroxycorticostéroïdes › 17-Hydroxycorticostéroïdes › Hydrocortisone › Inhibitors and fluorescent probes for protein...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Inhibitors and fluorescent probes for protein...