Influence of the Exposome on Skin Cancer.

La influencia del exposoma en el cáncer de piel.
Cáncer cutáneo no melanoma Cáncer de piel Exposoma Exposome Melanoma Non melanoma skin cáncer Skin cancer

Journal

Actas dermo-sifiliograficas
ISSN: 2173-5778
Titre abrégé: Actas Dermosifiliogr (Engl Ed)
Pays: Spain
ID NLM: 101777537

Informations de publication

Date de publication:
Historique:
received: 01 03 2020
revised: 01 04 2020
accepted: 05 04 2020
pubmed: 9 6 2020
medline: 25 6 2021
entrez: 9 6 2020
Statut: ppublish

Résumé

Skin cancer is the most frequent type of cancer in humans. While exposure to solar radiation is the most widely known and relevant causal factor, the different degrees of individual risk have not been fully elucidated. Epidemiological studies show how the risk of skin cancer is affected by other types of radiation (eg, ionizing radiation), pesticides, particulate matter in air pollution, toxins (eg, arsenic) in water and some foods. Some living entities, such as polyomavirus and human papillomavirus, can also cause specific types of cancer. Lastly, lifestyle factors such as stress, sleep, and exercise may play a role, although only a few studies shed light on these factors. The abovementioned factors make up the exposome of skin cancer, that is, the set of environmental exposures that, together with the genome and microbiome, determine the onset of disease.

Identifiants

pubmed: 32507282
pii: S0001-7310(20)30133-2
doi: 10.1016/j.ad.2020.04.008
pii:
doi:

Substances chimiques

Particulate Matter 0

Types de publication

Journal Article Review

Langues

eng spa

Sous-ensembles de citation

IM

Pagination

460-470

Informations de copyright

Copyright © 2020. Publicado por Elsevier España, S.L.U.

Auteurs

T Gracia-Cazaña (T)

Unidad de Dermatología, Hospital de Barbastro, Huesca, España. Electronic address: tamgracaz@gmail.com.

S González (S)

Departamento de Medicina y Especialidades Médicas, Instituto Ramón y Cajal de Investigación Sanitaria, Universidad de Alcalá, Madrid, España.

C Parrado (C)

Departamento de Histología y Patología, Universidad de Málaga, Málaga, España.

Á Juarranz (Á)

Departamento de Histología y Patología, Universidad de Málaga, Málaga, España.

Y Gilaberte (Y)

Departamento de Biología, Instituto Ramón y Cajal de Investigación Sanitaria, Universidad Autónoma de Madrid, Madrid, España; Servicio de Dermatología, Hospital Miguel Servet, Zaragoza, España.

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Classifications MeSH