The effect of green coffee extract supplementation on anthropometric measures in adults: A comprehensive systematic review and dose-response meta-analysis of randomized clinical trials.

Adult Body Mass Index Body Weight / drug effects Coffea / chemistry Dietary Supplements Dose-Response Relationship, Drug Humans Plant Extracts / administration & dosage Randomized Controlled Trials as Topic Waist Circumference / drug effects
Abdominal obesity Chlorogenic acid Green coffee Obesity

Journal

Complementary therapies in medicine
ISSN: 1873-6963
Titre abrégé: Complement Ther Med
Pays: Scotland
ID NLM: 9308777

Informations de publication

Date de publication:
Jun 2020
Historique:
received: 03 03 2020
revised: 19 04 2020
accepted: 30 04 2020
entrez: 9 6 2020
pubmed: 9 6 2020
medline: 3 11 2020
Statut: ppublish

Résumé

Two meta-analyses summarized data on the effects of green coffee extract (GCE) supplementation on anthropometric measures. However, the accuracy of those meta-analyses is uncertain due to several methodological limitations. Therefore, we aimed to conduct a comprehensive systematic review and dose-response meta-analysis to summarize all available evidence on the effects of GCE supplementation on anthropometric measures by considering the main limitations in the previous meta-analyses. We searched available online databases for relevant publications up to January 2020, using relevant keywords. All randomized clinical trials (RCTs) investigating the effects of GCE supplementation, compared with a control group, on anthropometric measures [including body weight, body mass index (BMI), body fat percentage, waist circumference (WC) and waist-to-hip ratio (WHR)] were included. After identifying 1871 studies from our initial search, 15 RCTs with a total sample size of 897 participants were included in the systematic review and meta-analysis. We found a significant reducing effect of GCE supplementation on body weight (weighted mean difference (WMD): -1.23, 95 % CI: -1.64, -0.82 kg,P < 0.001), BMI (WMD: -0.48, 95 % CI: -0.78, -0.18 kg/m We found that GCE supplementation had a beneficial effect on body weight, BMI and WC. It provides a cost-effective and safe alternative for the treatment of obesity. Additional well-designed studies are required to further confirm our findings.

Sections du résumé

BACKGROUND AND AIM OBJECTIVE
Two meta-analyses summarized data on the effects of green coffee extract (GCE) supplementation on anthropometric measures. However, the accuracy of those meta-analyses is uncertain due to several methodological limitations. Therefore, we aimed to conduct a comprehensive systematic review and dose-response meta-analysis to summarize all available evidence on the effects of GCE supplementation on anthropometric measures by considering the main limitations in the previous meta-analyses.
METHODS METHODS
We searched available online databases for relevant publications up to January 2020, using relevant keywords. All randomized clinical trials (RCTs) investigating the effects of GCE supplementation, compared with a control group, on anthropometric measures [including body weight, body mass index (BMI), body fat percentage, waist circumference (WC) and waist-to-hip ratio (WHR)] were included.
RESULTS RESULTS
After identifying 1871 studies from our initial search, 15 RCTs with a total sample size of 897 participants were included in the systematic review and meta-analysis. We found a significant reducing effect of GCE supplementation on body weight (weighted mean difference (WMD): -1.23, 95 % CI: -1.64, -0.82 kg,P < 0.001), BMI (WMD: -0.48, 95 % CI: -0.78, -0.18 kg/m
CONCLUSION CONCLUSIONS
We found that GCE supplementation had a beneficial effect on body weight, BMI and WC. It provides a cost-effective and safe alternative for the treatment of obesity. Additional well-designed studies are required to further confirm our findings.

Identifiants

DOI: 10.1016/j.ctim.2020.102424 PMID: 32507437
pubmed: 32507437
pii: S0965-2299(20)30444-1
doi: 10.1016/j.ctim.2020.102424
pii:
doi:

Substances chimiques

Plant Extracts 0

Types de publication

Journal Article Meta-Analysis Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

102424

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest All authors declared no personal or financial conflicts of interest.

Auteurs

Omid Asbaghi (O)

Nutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran. Electronic address: Asbaghi.omid@lums.ac.ir.

Mehdi Sadeghian (M)

Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Department of Nutrition, School of Allied Medical Sciences, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran. Electronic address: sadeghian.m@ajums.ac.ir.

Sepideh Rahmani (S)

Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address: ssv.rahmani@gmail.com.

Mahnaz Mardani (M)

Nutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran. Electronic address: mardani.m@lums.ac.ir.

Mahmoud Khodadost (M)

Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran. Electronic address: m.khodadost@behdasht.gov.ir.

Vahid Maleki (V)

Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: malekiv@tbzmed.ac.ir.

Aliyar Pirouzi (A)

Gerash University of Medical Sciences, Gerash, Iran. Electronic address: Pirouzi@gerums.ac.ir.

Sepide Talebi (S)

Student Research Committee, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address: s.talebi@nutr.mui.ac.ir.

Omid Sadeghi (O)

Gerash University of Medical Sciences, Gerash, Iran; Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran; Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: osadeghi@razi.tums.ac.ir.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › The effect of green coffee extract...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Mesures épidémiologiques › Biométrie › Anthropométrie › Indice de masse corporelle › The effect of green coffee extract...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Mensurations corporelles › Poids › The effect of green coffee extract...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Gentianales › Rubiaceae › Coffea › The effect of green coffee extract...
questionsmedicales.fr › Aliments et boissons › Aliments › Compléments alimentaires › The effect of green coffee extract...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › The effect of green coffee extract...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The effect of green coffee extract...
questionsmedicales.fr › Préparations pharmaceutiques › Extraits de plantes › The effect of green coffee extract...
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questionsmedicales.fr › Phénomènes physiologiques › Constitution physique › Poids et mesures du corps › Tour de taille › The effect of green coffee extract...