Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia-related risk factors.
abdominal aortic calcification score
chronic kidney disease
end stage renal disease
lateral plain radiograph of the abdomen
predialysis
vascular calcification
Journal
Experimental and therapeutic medicine
ISSN: 1792-0981
Titre abrégé: Exp Ther Med
Pays: Greece
ID NLM: 101531947
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
31
01
2020
accepted:
03
03
2020
entrez:
9
6
2020
pubmed:
9
6
2020
medline:
9
6
2020
Statut:
ppublish
Résumé
Cardiovascular disease is the main cause of morbidity and mortality in end-stage renal disease (ESRD) patients. Recent population based epidemiological studies demonstrated a correlation between reduced renal function and risk for all causes and cardiovascular mortality, 50% of patients dying before the commencement of renal replacement therapy. Vascular calcifications (VC) and arterial stiffness are major contributors to cardiovascular disease and are independent predictors of cardiovascular mortality in ESRD patients. Scarce information is available on the risk factors and prognosis of predialysis patients with VC. The aim of this study was to evaluate the contribution of traditional and uremia related risk factors to abdominal aortic calcification in predialysis patients. A single center, retrospective study was performed on 305 adult patients monitored at the Bucharest University Emergency Hospital for at least 6 months. Our study reports an increased incidence of VC in predialysis chronic kidney disease (CKD) patients, higher in those with advanced age, history of cardiovascular disease, osteoporosis, and declining renal function.
Identifiants
pubmed: 32509000
doi: 10.3892/etm.2020.8607
pii: ETM-0-0-8607
pmc: PMC7271689
doi:
Types de publication
Journal Article
Langues
eng
Pagination
97-102Informations de copyright
Copyright: © Timofte et al.
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