Interplay of multimorbidity and polypharmacy on a community dwelling frail elderly cohort in the peri-urban slums of Delhi, India.

Elderly frailty multimorbidity polypharmacy

Journal

Journal of family medicine and primary care
ISSN: 2249-4863
Titre abrégé: J Family Med Prim Care
Pays: India
ID NLM: 101610082

Informations de publication

Date de publication:
Mar 2020
Historique:
received: 26 10 2019
revised: 04 02 2020
accepted: 07 02 2020
entrez: 9 6 2020
pubmed: 9 6 2020
medline: 9 6 2020
Statut: epublish

Résumé

The United Nations Population Fund suggests that the number of elderly persons is expected to grow to 173 million by 2026. The aging phase is further made adverse by conditions such as failty, multimorbidity and polypharmacy. To assess the status and associates of frailty among elderly (>60 years) residing in a peri-urban slum area in Delhi by using the EDMONSTON Frail scale and evaluate the interplay of multimorbidity (MM) and polypharmacy (PP) on the frail pre-frail spectrum of the community-dwelling elderly cohort. A community study from Dec 2018 till July 2019 with a sample size of 300 participants who were willing and consented to the study. Frailty was assessed and the STOP criteria was used for PP assessment. There were 76 frail, 51 pre-frail, and 173 non-frail elderly. A higher prevalence (51%) of multimorbidity among the pre-frails and a higher probability (74%) of polypharmacy among the frails were found. Of the total in the frail-prefrail spectrum (127), 29.1% had multimorbidity (MM) and 39.4% had polypharmacy (PP). MM and PP were significantly higher among the old. Factors such as sex, marriage, loneliness, social circle, and education also had a positive bearing on the frailty-prefrailty spectrum. The working group had an increased (86%) probability of PP with statistical significance. Regression analysis depicted significant increased odds of MM and PP among female, illiterate, very old, lone, and single subjects. Thus, we recommend earlier and timely intervention for the frail-prefrail which can revert their adversities.

Identifiants

pubmed: 32509666
doi: 10.4103/jfmpc.jfmpc_945_19
pii: JFMPC-9-1647
pmc: PMC7266258
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1647-1655

Informations de copyright

Copyright: © 2020 Journal of Family Medicine and Primary Care.

Déclaration de conflit d'intérêts

There are no conflicts of interest.

Références

J Am Geriatr Soc. 2012 Aug;60(8):1487-92
pubmed: 22881367
Am J Geriatr Pharmacother. 2010 Jun;8(3):271-80
pubmed: 20624616
Fam Pract. 2009 Apr;26(2):79-80
pubmed: 19287000
Fam Pract. 2011 Oct;28(5):516-23
pubmed: 21436204
JAMA. 2005 Aug 10;294(6):716-24
pubmed: 16091574
Med J Aust. 2008 Jul 21;189(2):72-7
pubmed: 18637770
J Am Geriatr Soc. 2011 Jan;59(1):138-42
pubmed: 21198464
Cien Saude Colet. 2019 Jan;24(1):137-146
pubmed: 30698248
Clin Ther. 2008 Feb;30(2):419-27
pubmed: 18343279
Cien Saude Colet. 2016 Nov;21(11):3493-3498
pubmed: 27828582
Int J Nurs Stud. 2015 Aug;52(8):1362-74
pubmed: 25986959
Age Ageing. 2015 Jan;44(1):148-52
pubmed: 25355618
BMJ. 2003 Oct 11;327(7419):837
pubmed: 14551097
Ann Fam Med. 2009 Jul-Aug;7(4):357-63
pubmed: 19597174
PLoS One. 2014 Jul 21;9(7):e102149
pubmed: 25048354
J Am Geriatr Soc. 2015 Nov;63(11):2227-46
pubmed: 26446832
BMC Geriatr. 2018 Sep 14;18(1):212
pubmed: 30217182
BMC Health Serv Res. 2008 Jan 18;8:14
pubmed: 18205916
Menopause. 2012 May;19(5):569-75
pubmed: 22415564
Am J Geriatr Pharmacother. 2007 Dec;5(4):345-51
pubmed: 18179993
Expert Opin Drug Saf. 2014 Jan;13(1):57-65
pubmed: 24073682
Maturitas. 2014 Jan;77(1):78-84
pubmed: 24189222
J Clin Epidemiol. 1998 May;51(5):367-75
pubmed: 9619963
Ann Fam Med. 2012 Mar-Apr;10(2):142-51
pubmed: 22412006
BMC Geriatr. 2019 Oct 21;19(1):277
pubmed: 31638909
Age Ageing. 2015 Mar;44(2):213-8
pubmed: 25324330
BMJ Open. 2018 Mar 1;8(3):e018195
pubmed: 29496895
J Nutr Health Aging. 2012 Aug;16(8):732-5
pubmed: 23076517
Age Ageing. 2007 Nov;36(6):632-8
pubmed: 17881418
Health Qual Life Outcomes. 2004 Sep 20;2:51
pubmed: 15380021
BMC Health Serv Res. 2013 Aug 13;13:306
pubmed: 23938172
BMC Public Health. 2011 Feb 14;11:101
pubmed: 21320345
Am J Epidemiol. 2019 Sep 1;188(9):1627-1636
pubmed: 31274148
Ann Fam Med. 2005 May-Jun;3(3):223-8
pubmed: 15928225
J Clin Epidemiol. 1992 Oct;45(10):1045-51
pubmed: 1474400
J Comorb. 2013 Oct 8;3:4-9
pubmed: 29090140
J Gerontol A Biol Sci Med Sci. 2001 Mar;56(3):M146-56
pubmed: 11253156
BMJ Open. 2015 Oct 07;5(10):e007235
pubmed: 26446164
BMJ. 2007 May 19;334(7602):1016-7
pubmed: 17510108
Int J Equity Health. 2013 Aug 20;12:63
pubmed: 23962055
JAMA. 1996 Nov 13;276(18):1473-9
pubmed: 8903258
J Gerontol Nurs. 2005 Sep;31(9):4-11
pubmed: 16190007
Indian J Pharmacol. 2017 Jan-Feb;49(1):16-20
pubmed: 28458417

Auteurs

Meely Panda (M)

Asst. Prof, Department of Community Medicine, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India.

Rambha Pathak (R)

Professor, Department of Community Medicine, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India.

Farzana Islam (F)

Associate Prof, Department of Community Medicine, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India.

Rashmi Agarwalla (R)

Asst. Prof, Department of Community Medicine, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India.

Vishal Singh (V)

Residents, Department of Community Medicine, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India.

Farishta Singh (F)

Residents, Department of Community Medicine, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India.

Classifications MeSH