Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals.


Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
22 May 2020
Historique:
entrez: 9 6 2020
pubmed: 9 6 2020
medline: 9 6 2020
Statut: epublish

Résumé

During the COVID-19 pandemic, SARS-CoV-2 infected millions of people and claimed hundreds of thousands of lives. Virus entry into cells depends on the receptor binding domain (RBD) of the SARS-CoV-2 spike protein (S). Although there is no vaccine, it is likely that antibodies will be essential for protection. However, little is known about the human antibody response to SARS-CoV-2

Identifiants

pubmed: 32511384
doi: 10.1101/2020.05.13.092619
pmc: PMC7263513
pii:
doi:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI078788
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI091707
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001866
Pays : United States
Organisme : NIAID NIH HHS
ID : R37 AI064003
Pays : United States
Organisme : NIAID NIH HHS
ID : U19 AI111825
Pays : United States
Organisme : NIAID NIH HHS
ID : P50 AI150464
Pays : United States

Commentaires et corrections

Type : UpdateIn

Déclaration de conflit d'intérêts

Declaration of conflict: In connection with this work The Rockefeller University has filed a provisional patent application on which D.F.R. and M.C.N. are inventors.

Références

Nature. 2020 Jul;583(7815):290-295
pubmed: 32422645
Cell Host Microbe. 2016 Sep 14;20(3):392-405
pubmed: 27631702
Nat Methods. 2017 Mar;14(3):290-296
pubmed: 28165473
Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7981-7989
pubmed: 32209664
PLoS Med. 2006 Jul;3(7):e237
pubmed: 16796401
J Immunol Methods. 2008 Jan 1;329(1-2):112-24
pubmed: 17996249
Nat Rev Microbiol. 2013 Dec;11(12):836-48
pubmed: 24217413
Nat Rev Immunol. 2020 Jun;20(6):339-341
pubmed: 32317716
Nature. 2014 Dec 18;516(7531):418-22
pubmed: 25296253
Nature. 2019 Feb;566(7744):393-397
pubmed: 30664748
Cell. 2020 Apr 16;181(2):271-280.e8
pubmed: 32142651
J Exp Med. 2014 Nov 17;211(12):2361-72
pubmed: 25385756
PLoS One. 2012;7(11):e49774
pubmed: 23226220
Sci Immunol. 2018 Feb 16;3(20):
pubmed: 29453292
Science. 2017 Nov 17;358(6365):865-866
pubmed: 29146795
Immunity. 2019 Jun 18;50(6):1513-1529.e9
pubmed: 31126879
Immunity. 2007 Feb;26(2):205-13
pubmed: 17306569
J Immunol Methods. 2020 Mar;478:112734
pubmed: 31866284
Nature. 2009 Apr 2;458(7238):636-40
pubmed: 19287373
Cell. 2020 Apr 16;181(2):281-292.e6
pubmed: 32155444
NPJ Vaccines. 2017 Jul 10;2:19
pubmed: 29263875
Trends Immunol. 2020 May;41(5):355-359
pubmed: 32249063
Nat Protoc. 2016 Oct;11(10):1908-1923
pubmed: 27658009
J Mol Biol. 1982 May 5;157(1):105-32
pubmed: 7108955
J Pathol. 2015 Jan;235(2):185-95
pubmed: 25270030
Cell. 2017 May 04;169(4):597-609.e11
pubmed: 28475892
Science. 2020 May 8;368(6491):630-633
pubmed: 32245784
J Virol. 1986 Aug;59(2):284-91
pubmed: 3016298
Biophys J. 1985 Jan;47(1):61-70
pubmed: 3978191
Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12123-8
pubmed: 17620608
Immunol Rev. 2017 Jan;275(1):285-295
pubmed: 28133801
Science. 2011 Sep 16;333(6049):1633-7
pubmed: 21764753
J Struct Biol. 2005 Oct;152(1):36-51
pubmed: 16182563
Bioinformatics. 2015 Oct 15;31(20):3356-8
pubmed: 26069265
Nucleic Acids Res. 2013 Jul;41(Web Server issue):W34-40
pubmed: 23671333
Clin Vaccine Immunol. 2010 Jul;17(7):1055-65
pubmed: 20463105
Nat Med. 2019 Oct;25(10):1589-1600
pubmed: 31591605
PLoS One. 2016 Aug 11;11(8):e0160853
pubmed: 27513338
J Struct Biol. 2007 Jan;157(1):281-7
pubmed: 16963278
Cell. 2019 Feb 21;176(5):1026-1039.e15
pubmed: 30712865

Auteurs

Davide F Robbiani (DF)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Christian Gaebler (C)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Frauke Muecksch (F)

Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.

Julio C C Lorenzi (JCC)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Zijun Wang (Z)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Alice Cho (A)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Marianna Agudelo (M)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Christopher O Barnes (CO)

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

Anna Gazumyan (A)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Shlomo Finkin (S)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Thomas Hagglof (T)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Thiago Y Oliveira (TY)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Charlotte Viant (C)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Arlene Hurley (A)

Hospital Program Direction, The Rockefeller University, New York, NY 10065, USA.

Hans-Heinrich Hoffmann (HH)

Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.

Katrina G Millard (KG)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Rhonda G Kost (RG)

Hospital Clinical Research Office, The Rockefeller University, New York, NY 10065, USA.

Melissa Cipolla (M)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Kristie Gordon (K)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Filippo Bianchini (F)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Spencer T Chen (ST)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Victor Ramos (V)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Roshni Patel (R)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Juan Dizon (J)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Irina Shimeliovich (I)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Pilar Mendoza (P)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Harald Hartweger (H)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Lilian Nogueira (L)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Maggi Pack (M)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Jill Horowitz (J)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Fabian Schmidt (F)

Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.

Yiska Weisblum (Y)

Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.

Eleftherios Michailidis (E)

Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.

Alison W Ashbrook (AW)

Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.

Eric Waltari (E)

Chan Zuckerberg Biohub, 499 Illinois Street, San Francisco, CA 94158, USA.

John E Pak (JE)

Chan Zuckerberg Biohub, 499 Illinois Street, San Francisco, CA 94158, USA.

Kathryn E Huey-Tubman (KE)

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

Nicholas Koranda (N)

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

Pauline R Hoffman (PR)

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

Anthony P West (AP)

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

Charles M Rice (CM)

Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.

Theodora Hatziioannou (T)

Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.

Pamela J Bjorkman (PJ)

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

Paul D Bieniasz (PD)

Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.
Howard Hughes Medical Institute.

Marina Caskey (M)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Michel C Nussenzweig (MC)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Howard Hughes Medical Institute.

Classifications MeSH