Inhibition of Fatty Acid Oxidation as a New Target To Treat Primary Amoebic Meningoencephalitis.

Amphotericin B Animals Central Nervous System Protozoal Infections Fatty Acids Meningoencephalitis Naegleria Naegleria fowleri
Naegleria fowleri Naegleria gruberi drug targets energy metabolism lipid metabolism therapy thioridazine treatment

Journal

Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061

Informations de publication

Date de publication:
22 07 2020
Historique:
received: 26 02 2020
accepted: 03 06 2020
pubmed: 10 6 2020
medline: 22 6 2021
entrez: 10 6 2020
Statut: epublish

Résumé

Primary amoebic meningoencephalitis (PAM) is a rapidly fatal infection caused by the free-living amoeba

Identifiants

DOI: 10.1128/AAC.00344-20 PMID: 32513800 PMC: PMC7526813
pubmed: 32513800
pii: AAC.00344-20
doi: 10.1128/AAC.00344-20
pmc: PMC7526813
pii:
doi:

Substances chimiques

Fatty Acids 0
Amphotericin B 7XU7A7DROE

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2020 Sarink et al.

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Auteurs

Maarten J Sarink (MJ)

Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands.

Aloysius G M Tielens (AGM)

Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands.
Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.

Annelies Verbon (A)

Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands.

Robert Sutak (R)

Department of Parasitology, Faculty of Science, Charles University, BIOCEV, Vestec, Czech Republic.

Jaap J van Hellemond (JJ)

Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands j.vanhellemond@erasmusmc.nl.
ORCID: 0000-0003-4862-7796

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Lactones › Amphotéricine B › Inhibition of Fatty Acid Oxidation as a New...
questionsmedicales.fr › Eucaryotes › Animaux › Inhibition of Fatty Acid Oxidation as a New...
questionsmedicales.fr › Maladies du système nerveux › Maladies du système nerveux central › Infections du système nerveux central › Infections parasitaires du système nerveux central › Protozooses du système nerveux central › Inhibition of Fatty Acid Oxidation as a New...
questionsmedicales.fr › Lipides › Acides gras › Inhibition of Fatty Acid Oxidation as a New...
questionsmedicales.fr › Maladies du système nerveux › Méningite › Méningoencéphalite › Inhibition of Fatty Acid Oxidation as a New...
questionsmedicales.fr › Eucaryotes › Amoebozoa › Lobosea › Schizopyrenida › Naegleria › Inhibition of Fatty Acid Oxidation as a New...
questionsmedicales.fr › Eucaryotes › Amoebozoa › Lobosea › Schizopyrenida › Naegleria › Naegleria fowleri › Inhibition of Fatty Acid Oxidation as a New...