Patients' Measurement Priorities for Remote Measurement Technologies to Aid Chronic Health Conditions: Qualitative Analysis.


Journal

JMIR mHealth and uHealth
ISSN: 2291-5222
Titre abrégé: JMIR Mhealth Uhealth
Pays: Canada
ID NLM: 101624439

Informations de publication

Date de publication:
10 06 2020
Historique:
received: 26 06 2019
accepted: 15 12 2019
revised: 31 10 2019
entrez: 11 6 2020
pubmed: 11 6 2020
medline: 28 4 2021
Statut: epublish

Résumé

Remote measurement technology (RMT), including the use of mobile phone apps and wearable devices, may provide the opportunity for real-world assessment and intervention that will streamline clinical input for years to come. In order to establish the benefits of this approach, we need to operationalize what is expected in terms of a successful measurement. We focused on three clinical long-term conditions where a novel case has been made for the benefits of RMT: major depressive disorder (MDD), multiple sclerosis (MS), and epilepsy. The aim of this study was to conduct a consultation exercise on the clinical end point or outcome measurement priorities for RMT studies, drawing on the experiences of people with chronic health conditions. A total of 24 participants (16/24 women, 67%), ranging from 28 to 65 years of age, with a diagnosis of one of three chronic health conditions-MDD, MS, or epilepsy-took part in six focus groups. A systematic thematic analysis was used to extract themes and subthemes of clinical end point or measurement priorities. The views of people with MDD, epilepsy, and MS differed. Each group highlighted unique measurements of importance, relevant to their specific needs. Although there was agreement that remote measurement could be useful for tracking symptoms of illness, some symptoms were specific to the individual groups. Measuring signs of wellness was discussed more by people with MDD than by people with MS and epilepsy. However, overlap did emerge when considering contextual factors, such as life events and availability of support (MDD and epilepsy) as well as ways of coping (epilepsy and MS). This is a unique study that puts patients' views at the forefront of the design of a clinical study employing novel digital resources. In all cases, measuring symptom severity is key; people want to know when their health is getting worse. Second, symptom severity needs to be placed into context. A holistic approach that, in some cases, considers signs of wellness as well as illness, should be the aim of studies employing RMT to understand the health of people with chronic conditions.

Sections du résumé

BACKGROUND
Remote measurement technology (RMT), including the use of mobile phone apps and wearable devices, may provide the opportunity for real-world assessment and intervention that will streamline clinical input for years to come. In order to establish the benefits of this approach, we need to operationalize what is expected in terms of a successful measurement. We focused on three clinical long-term conditions where a novel case has been made for the benefits of RMT: major depressive disorder (MDD), multiple sclerosis (MS), and epilepsy.
OBJECTIVE
The aim of this study was to conduct a consultation exercise on the clinical end point or outcome measurement priorities for RMT studies, drawing on the experiences of people with chronic health conditions.
METHODS
A total of 24 participants (16/24 women, 67%), ranging from 28 to 65 years of age, with a diagnosis of one of three chronic health conditions-MDD, MS, or epilepsy-took part in six focus groups. A systematic thematic analysis was used to extract themes and subthemes of clinical end point or measurement priorities.
RESULTS
The views of people with MDD, epilepsy, and MS differed. Each group highlighted unique measurements of importance, relevant to their specific needs. Although there was agreement that remote measurement could be useful for tracking symptoms of illness, some symptoms were specific to the individual groups. Measuring signs of wellness was discussed more by people with MDD than by people with MS and epilepsy. However, overlap did emerge when considering contextual factors, such as life events and availability of support (MDD and epilepsy) as well as ways of coping (epilepsy and MS).
CONCLUSIONS
This is a unique study that puts patients' views at the forefront of the design of a clinical study employing novel digital resources. In all cases, measuring symptom severity is key; people want to know when their health is getting worse. Second, symptom severity needs to be placed into context. A holistic approach that, in some cases, considers signs of wellness as well as illness, should be the aim of studies employing RMT to understand the health of people with chronic conditions.

Identifiants

pubmed: 32519975
pii: v8i6e15086
doi: 10.2196/15086
pmc: PMC7315360
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e15086

Informations de copyright

©Sara Simblett, Faith Matcham, Hannah Curtis, Ben Greer, Ashley Polhemus, Jan Novák, Jose Ferrao, Peter Gamble, Matthew Hotopf, Vaibhav Narayan, Til Wykes, Remote Assessment Of Disease And Relapse – Central Nervous System (RADAR-CNS) Consortium. Originally published in JMIR mHealth and uHealth (http://mhealth.jmir.org), 10.06.2020.

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Auteurs

Sara Simblett (S)

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

Faith Matcham (F)

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

Hannah Curtis (H)

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

Ben Greer (B)

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

Ashley Polhemus (A)

Merck Research Labs IT, Merck Sharpe & Dohme, Prague, Czech Republic.

Jan Novák (J)

Merck Research Labs IT, Merck Sharpe & Dohme, Prague, Czech Republic.

Jose Ferrao (J)

Merck Research Labs IT, Merck Sharpe & Dohme, Prague, Czech Republic.

Peter Gamble (P)

Merck Research Labs IT, Merck Sharpe & Dohme, Prague, Czech Republic.

Matthew Hotopf (M)

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

Vaibhav Narayan (V)

Janssen Pharmaceuticals, LLC, Titusville, NJ, United States.

Til Wykes (T)

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
RADAR-CNS, London, United Kingdom.

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