"Noninfective Endocarditis": A Case Report of Hereditary Coagulation Disorders in a 28-Year-Old Male.

acute coronary syndrome anticoagulation genetic disorders thrombosis ultrasound valve replacement

Journal

Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402

Informations de publication

Date de publication:
08 Jun 2020
Historique:
received: 27 05 2020
revised: 04 06 2020
accepted: 05 06 2020
entrez: 12 6 2020
pubmed: 12 6 2020
medline: 12 6 2020
Statut: epublish

Résumé

We report a case of a young male who presented with acute limb ischemia after sport. With no prior history of disease, a non-infective endocarditis of the native aortic valve was diagnosed. After surgical valve replacement, the patient suffered from acute myocardial ischemia under phenprocoumon therapy. Anti-coagulant monitoring was subsequently changed to Factor II analysis after a rare Factor VII deficiency and prothrombin mutation (G20210A) was diagnosed.

Identifiants

pubmed: 32521783
pii: diagnostics10060384
doi: 10.3390/diagnostics10060384
pmc: PMC7345217
pii:
doi:

Types de publication

Case Reports

Langues

eng

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Auteurs

Gregory Reid (G)

Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.

Luca Koechlin (L)

Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.

Oliver Reuthebuch (O)

Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.

Florian Rüter (F)

Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.

Helmut Hopfer (H)

Institute of Medical Genetics and Pathology, University Hospital Basel, 4031 Basel, Switzerland.

Friedrich Eckstein (F)

Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.

David Santer (D)

Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.

Classifications MeSH