Genetic Diversity and Signatures of Selection in a Native Italian Horse Breed Based on SNP Data.
IBH
LCORL
MC1R
ROH
autochthonous
coat color
conservation
genomics
horse
selection scan
Journal
Animals : an open access journal from MDPI
ISSN: 2076-2615
Titre abrégé: Animals (Basel)
Pays: Switzerland
ID NLM: 101635614
Informations de publication
Date de publication:
08 Jun 2020
08 Jun 2020
Historique:
received:
14
05
2020
revised:
01
06
2020
accepted:
04
06
2020
entrez:
12
6
2020
pubmed:
12
6
2020
medline:
12
6
2020
Statut:
epublish
Résumé
Horses are nowadays mainly used for sport and leisure activities, and several local breeds, traditionally used in agriculture, have been exposed to a dramatic loss in population size and genetic diversity. The loss of genetic diversity negatively impacts individual fitness and reduces the potential long-term survivability of a breed. Recent advances in molecular biology and bioinformatics have allowed researchers to explore biodiversity one step further. This study aimed to evaluate the loss of genetic variability and identify genomic regions under selection pressure in the Bardigiano breed based on GGP Equine70k SNP data. The effective population size based on Linkage Disequilibrium (N
Identifiants
pubmed: 32521830
pii: ani10061005
doi: 10.3390/ani10061005
pmc: PMC7341496
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : PSRN 2016-2019 "Biodiversità-Sottomisura 355 10.2-Progetto Equinbio-Innovazione e Biodiversità per gli equidi
ID : PSRN 2016-2019
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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