Medical cannabis in the UK: From principle to practice.


Journal

Journal of psychopharmacology (Oxford, England)
ISSN: 1461-7285
Titre abrégé: J Psychopharmacol
Pays: United States
ID NLM: 8907828

Informations de publication

Date de publication:
09 2020
Historique:
pubmed: 12 6 2020
medline: 5 11 2021
entrez: 12 6 2020
Statut: ppublish

Résumé

In the UK, medical cannabis was approved in November 2018, leading many patients to believe that the medicine would now be available on the NHS. Yet, to date, there have been only 12 NHS prescriptions and less than 60 prescriptions in total. In marked contrast, a recent patient survey by the Centre for Medical Cannabis (Couch, 2020) found 1.4 m people are using illicit cannabis for medical problems. Such a mismatch between demand and supply is rare in medicine. This article outlines some of the current controversies about medical cannabis that underpin this disparity, beginning by contrasting current medical evidence from research studies with patient-reported outcomes. Although definite scientific evidence is scarce for most conditions, there is significant patient demand for access to medical cannabis. This disparity poses a challenge for prescribers, and there are many concerns of physicians when deciding if, and how, to prescribe medical cannabis which still need to be addressed. Potential solutions are outlined as to how the medical profession and regulators could respond to the strong demand from patients and families for access to medical cannabis to treat chronic illnesses when there is often a limited scientific evidence base on whether and how to use it in many of these conditions. There is a need to maximise both clinical research and patient benefit, in a safe, cautious and ethical manner, so that those patients for whom cannabis is shown to be effective can access it. We hope our discussion and outlines for future progress offer a contribution to this process.

Sections du résumé

BACKGROUND
In the UK, medical cannabis was approved in November 2018, leading many patients to believe that the medicine would now be available on the NHS. Yet, to date, there have been only 12 NHS prescriptions and less than 60 prescriptions in total. In marked contrast, a recent patient survey by the Centre for Medical Cannabis (Couch, 2020) found 1.4 m people are using illicit cannabis for medical problems.
AIMS
Such a mismatch between demand and supply is rare in medicine. This article outlines some of the current controversies about medical cannabis that underpin this disparity, beginning by contrasting current medical evidence from research studies with patient-reported outcomes.
OUTCOMES
Although definite scientific evidence is scarce for most conditions, there is significant patient demand for access to medical cannabis. This disparity poses a challenge for prescribers, and there are many concerns of physicians when deciding if, and how, to prescribe medical cannabis which still need to be addressed. Potential solutions are outlined as to how the medical profession and regulators could respond to the strong demand from patients and families for access to medical cannabis to treat chronic illnesses when there is often a limited scientific evidence base on whether and how to use it in many of these conditions.
CONCLUSIONS
There is a need to maximise both clinical research and patient benefit, in a safe, cautious and ethical manner, so that those patients for whom cannabis is shown to be effective can access it. We hope our discussion and outlines for future progress offer a contribution to this process.

Identifiants

pubmed: 32522058
doi: 10.1177/0269881120926677
pmc: PMC7436434
doi:

Substances chimiques

Cannabinoids 0
Medical Marijuana 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

931-937

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Auteurs

Anne Katrin Schlag (AK)

Drug Science, London, UK.
King's College London, London, UK.

David S Baldwin (DS)

Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
University of Cape Town, Cape Town, South Africa.

Michael Barnes (M)

University of Newcastle, Newcastle upon Tyne, UK.

Steve Bazire (S)

School of Pharmacy, University of East Anglia, Norwich, UK.

Rachel Coathup (R)

University of Manchester, Manchester, UK.

H Valerie Curran (HV)

Clinical, Education and Health Psychology, University College London, London, UK.

Rupert McShane (R)

Interventional Psychiatry Service, Oxford Health NHS Foundation Trust, Oxford, UK.

Lawrence D Phillips (LD)

Department of Management, London School of Economics & Political Science, London, UK.

Ilina Singh (I)

Department of Psychiatry, University of Oxford, Oxford, UK.

David J Nutt (DJ)

Department of Brain Sciences, Imperial College London, London, UK.

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Classifications MeSH