Rare case of metastatic small cell carcinoma of the nasopharynx to the pancreas.
Carcinoma, Small Cell
/ pathology
Chemoradiotherapy
/ methods
Cholecystectomy
/ methods
Endoscopic Ultrasound-Guided Fine Needle Aspiration
/ methods
Female
Fluorodeoxyglucose F18
/ pharmacology
Humans
Middle Aged
Nasopharynx
/ diagnostic imaging
Neoplasm Staging
Pancreas
/ diagnostic imaging
Pancreatectomy
/ methods
Pancreatic Neoplasms
/ pathology
Pharyngeal Neoplasms
/ pathology
Positron-Emission Tomography
/ methods
Prognosis
Radiopharmaceuticals
/ pharmacology
Splenectomy
/ methods
cancer intervention
head and neck cancer
pancreas and biliary tract
pancreatic cancer
surgical oncology
Journal
BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291
Informations de publication
Date de publication:
09 Jun 2020
09 Jun 2020
Historique:
entrez:
12
6
2020
pubmed:
12
6
2020
medline:
13
2
2021
Statut:
epublish
Résumé
We present a 49-year-old woman with a history of an unresectable nasopharyngeal small cell carcinoma (SCC) who was treated with concurrent chemotherapy and radiation therapy. On surveillance positron emission tomography scan 14 months after diagnosis, her primary tumour appeared stable, but there was fludeoxyglucose uptake in the pancreas. A CT scan demonstrated a 3.4×2.1 cm ill-defined soft tissue mass at the tail of the pancreas, which was concerning for adenocarcinoma. However, further workup including endoscopic ultrasound and fine needle aspiration confirmed the mass to be a metastasis from her nasopharyngeal SCC. Because there have been no previously reported cases of a metastatic small cell carcinoma to the pancreas, there are no data about prognosis. Thus treatment options were tailored to the patient. Distal pancreatectomy, splenectomy and cholecystectomy were performed. The patient recovered from surgery without complication.
Identifiants
pubmed: 32522725
pii: 13/6/e235054
doi: 10.1136/bcr-2020-235054
pmc: PMC7287496
pii:
doi:
Substances chimiques
Radiopharmaceuticals
0
Fluorodeoxyglucose F18
0Z5B2CJX4D
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
Références
Head Neck. 2015 May;37(5):707-15
pubmed: 24596175
Cancer. 2010 Feb 15;116(4):888-95
pubmed: 20052730
BMJ Open. 2015 Jan 14;5(1):e006440
pubmed: 25588780
Radiographics. 2015 Jan-Feb;35(1):152-63
pubmed: 25590395
BMC Cancer. 2009 Jun 29;9:209
pubmed: 19563623
Anticancer Res. 2012 Apr;32(4):1449-52
pubmed: 22493384
Virchows Arch. 2004 Jun;444(6):527-35
pubmed: 15057558
Tumori. 2003 May-Jun;89(3):274-7
pubmed: 12908782
Med Oncol. 2014 Oct;31(10):187
pubmed: 25151532
Semin Oncol. 2007 Feb;34(1):30-8
pubmed: 17270663
Autops Case Rep. 2017 Mar 30;7(1):31-35
pubmed: 28536685