Is Albumin Predictor of Mortality in COVID-19?
COVID-19
albumin
mortality
Journal
Antioxidants & redox signaling
ISSN: 1557-7716
Titre abrégé: Antioxid Redox Signal
Pays: United States
ID NLM: 100888899
Informations de publication
Date de publication:
10 07 2021
10 07 2021
Historique:
pubmed:
12
6
2020
medline:
12
6
2020
entrez:
12
6
2020
Statut:
ppublish
Résumé
Coronavirus 2019 (COVID-19) is a pandemic associated with a high risk of mortality. Human serum albumin (HSA) is an acute phase reactant with antioxidant property; however, its behavior and impact on survival in COVID-19 patients have never been studied so far. Among 319 COVID-19 patients followed up for a median of 19 days, 64 died. Compared with survivors, nonsurvivors had more prevalence of intensive care unit (ICU) admission, chronic obstructive pulmonary disease (COPD), heart failure, elevated levels of D-dimer, high-sensitivity C reactive protein (hs-CRP) and troponins, and lower values of albumin. At the Cox regression analysis, albumin (hazard ratio [HR]: 0.38, 95% confidence interval [CI]: 0.23-0.63,
Identifiants
pubmed: 32524832
doi: 10.1089/ars.2020.8142
doi:
Types de publication
News
Langues
eng
Sous-ensembles de citation
IM