Sex-Related Differences in the Effects of Sports-Related Concussion: A Review.

Athletic Injuries / diagnostic imaging Brain Concussion / diagnostic imaging Female Humans Male Neuroimaging Prognosis Severity of Illness Index Sex Characteristics
Concussion neuroimaging sex differences

Journal

Journal of neuroimaging : official journal of the American Society of Neuroimaging
ISSN: 1552-6569
Titre abrégé: J Neuroimaging
Pays: United States
ID NLM: 9102705

Informations de publication

Date de publication:
07 2020
Historique:
received: 08 04 2020
accepted: 30 04 2020
pubmed: 14 6 2020
medline: 16 2 2021
entrez: 14 6 2020
Statut: ppublish

Résumé

Sports-related concussion is a serious health challenge, and females are at higher risk of sustaining a sports-related concussion compared to males. Although there are many studies that investigate outcomes following concussion, females remain an understudied population, despite representing a large proportion of the organized sports community. In this review, we provide a summary of studies that investigate sex-related differences in outcome following sports-related concussion. Moreover, we provide an introduction to the methods used to study sex-related differences after sports-related concussion, including common clinical and cognitive measures, neuroimaging techniques, as well as biomarkers. A literature search inclusive of articles published to March 2020 was performed using PubMed. The studies were reviewed and discussed with regard to the methods used. Findings from these studies remain mixed with regard to the effect of sex on clinical symptoms, concussion-related alterations in brain structure and function, and recovery trajectories. Nonetheless, there is initial evidence to suggest that sex-related differences following concussion are important to consider in efforts to develop objective biomarkers for the diagnosis and prognosis of concussion. Additional studies on this topic are, however, clearly needed to improve our understanding of sex-related differences following concussion, as well as to understand their neurobiological underpinnings. Such studies will help pave the way toward more personalized clinical management and treatment of sports-related concussion.

Identifiants

DOI: 10.1111/jon.12726 PMID: 32533752 PMC: PMC8221087
pubmed: 32533752
doi: 10.1111/jon.12726
pmc: PMC8221087
mid: NIHMS1715530
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

387-409

Subventions

Organisme : RRD VA
ID : I01 RX000928
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS100952
Pays : United States
Organisme : NINDS NIH HHS
ID : U01 NS093334
Pays : United States
Organisme : NIH HHS
ID : U01 NS 093334
Pays : United States

Informations de copyright

© 2020 The Authors. Journal of Neuroimaging published by Wiley Periodicals LLC on behalf of American Society of Neuroimaging.

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Auteurs

Inga K Koerte (IK)

Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
cBRAIN, Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Ludwig-Maximilian-University, Munich, Germany.
Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
ORCID: 0000-0003-1281-9286

Vivian Schultz (V)

Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
cBRAIN, Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Ludwig-Maximilian-University, Munich, Germany.

Valerie J Sydnor (VJ)

Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

David R Howell (DR)

Sports Medicine Center, Children's Hospital Colorado, Aurora, CO.
Department of Orthopedics, University of Colorado School of Medicine, Aurora, CO.
ORCID: 0000-0002-2955-0191

Jeffrey P Guenette (JP)

Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

Emily Dennis (E)

Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Department of Neurology, University of Utah, Salt Lake City, UT.

Janna Kochsiek (J)

Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
cBRAIN, Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Ludwig-Maximilian-University, Munich, Germany.

David Kaufmann (D)

Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
cBRAIN, Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Ludwig-Maximilian-University, Munich, Germany.
Department of Radiology, Charité Universitätsmedizin, Berlin, Germany.

Nico Sollmann (N)

Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
cBRAIN, Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Ludwig-Maximilian-University, Munich, Germany.
Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
TUM-Neuroimaging Center, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
ORCID: 0000-0002-8120-2223

Stefania Mondello (S)

Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy.
Oasi Research Institute-IRCCS, Troina, Italy.

Martha E Shenton (ME)

Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
VA Boston Healthcare System, Boston, MA.

Alexander P Lin (AP)

Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Center for Clinical Spectroscopy, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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questionsmedicales.fr › Plaies et blessures › Traumatismes sportifs › Sex-Related Differences in the Effects of...
questionsmedicales.fr › Plaies et blessures › Plaies non pénétrantes › Traumatismes crâniens fermés › Commotion de l'encéphale › Sex-Related Differences in the Effects of...
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